Diffuse large B-cell lymphoma in the elderly: Impact of prognosis, comorbidities, geriatric assessment, and supportive care on clinical practice. An International Society of Geriatric Oncology (SIOG) expert position paper Journal Article

  

Authors:	Morrison, V. A.; Hamlin, P.; Soubeyran, P.; Stauder, R.; Wadhwa, P.; Aapro, M.; Lichtman, S.
Article Title:	Diffuse large B-cell lymphoma in the elderly: Impact of prognosis, comorbidities, geriatric assessment, and supportive care on clinical practice. An International Society of Geriatric Oncology (SIOG) expert position paper
Abstract:	Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma in the elderly, and is increasing in incidence. Although significant therapeutic advances have recently been made in the care of older patients with DLBCL, based upon results of randomized clinical trials, many older patients are not eligible for such trials due to comorbidities and functional decline. Pre-treatment evaluation of older patients to ascertain potential tolerance to therapy is especially important in therapeutic decisions for this population. Evaluation by performance status alone is insufficient, especially in the elderly, and consideration of the impact of comorbidities and functional/social decline needs to be included in such assessment. As part of an International Society of Geriatric Oncology (SIOG) task force, the issues of prognosis, comorbidities, geriatric assessment, and supportive care measures in older patients with DLBCL will be reviewed, and recommendations for assessment and allied care made. © 2014 .
Keywords:	large cell lymphoma; elderly; geriatric assessment; frailty; comorbidities
Journal Title:	Journal of Geriatric Oncology
Volume:	6
Issue:	2
ISSN:	1879-4068
Publisher:	Elsevier Inc.
Date Published:	2015-03-01
Start Page:	141
End Page:	152
Language:	English
DOI:	10.1016/j.jgo.2014.11.004
PROVIDER:	scopus
PUBMED:	25491101
DOI/URL:	http://www.scopus.com/inward/record.url?eid=2-s2.0-84925248601&partnerID=40&md5=4da58ef8a7c56d9f8aadfbc203758c7a
Notes:	Export Date: 2 April 2015 -- Source: Scopus

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