Esophageal and esophagogastric junction cancers, version 1.2015 Journal Article
| Authors: | Ajani, J. A.; D'Amico, T. A.; Almhanna, K.; Bentrem, D. J.; Besh, S.; Chao, J.; Das, P.; Denlinger, C.; Fanta, P.; Fuchs, C. S.; Gerdes, H.; Glasgow, R. E.; Hayman, J. A.; Hochwald, S.; Hofstetter, W. L.; Ilson, D. H.; Jaroszewski, D.; Jasperson, K.; Keswani, R. N.; Kleinberg, L. R.; Korn, W. M.; Leong, S.; Lockhart, A. C.; Mulcahy, M. F.; Orringer, M. B.; Posey, J. A.; Poultsides, G. A.; Sasson, A. R.; Scott, W. J.; Strong, V. E.; Varghese, T. K.; Washington, M. K.; Willett, C. G.; Wright, C. D.; Zelman, D.; McMillian, N.; Sundar, H. |
| Article Title: | Esophageal and esophagogastric junction cancers, version 1.2015 |
| Abstract: | Esophageal cancer is the sixth most common cause of cancer deaths worldwide. Adenocarcinoma is more common in North America and Western European countries, originating mostly in the lower third of the esophagus, which often involves the esophagogastric junction (EGJ). Recent randomized trials have shown that the addition of preoperative chemoradiation or perioperative chemotherapy to surgery significantly improves survival in patients with resectable cancer. Targeted therapies with trastuzumab and ramucirumab have produced encouraging results in the treatment of advanced or metastatic EGJ adenocarcinomas. Multidisciplinary team management is essential for patients with esophageal and EGJ cancers. This portion of the NCCN Guidelines for Esophageal and EGJ Cancers discusses management of locally advanced adenocarcinoma of the esophagus and EGJ. © National Comprehensive Cancer Network, Inc. |
| Keywords: | cancer chemotherapy; cancer surgery; review; cancer recurrence; advanced cancer; multimodality cancer therapy; cancer patient; cancer radiotherapy; postoperative care; preoperative care; cancer staging; follow up; antineoplastic agent; gene overexpression; metastasis; epidermal growth factor receptor 2; practice guideline; cancer mortality; cause of death; stomach cancer; perioperative period; esophagus cancer; chemoradiotherapy; lower esophagus sphincter; oncogene neu; molecularly targeted therapy; esophagogastric junction cancer; human |
| Journal Title: | Journal of the National Comprehensive Cancer Network |
| Volume: | 13 |
| Issue: | 2 |
| ISSN: | 1540-1405 |
| Publisher: | Harborside Press |
| Date Published: | 2015-02-01 |
| Start Page: | 194 |
| End Page: | 227 |
| Language: | English |
| PROVIDER: | scopus |
| PUBMED: | 25691612 |
| DOI/URL: | |
| Notes: | Export Date: 2 April 2015 -- Source: Scopus |
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