Surgical principles for optimal treatment of esophagogastric junction adenocarcinoma Review


Authors: Nobel, T.; Molena, D.
Review Title: Surgical principles for optimal treatment of esophagogastric junction adenocarcinoma
Abstract: The incidence of esophagogastric junction (EGJ) adenocarcinoma is increasing worldwide. Management of these tumors remains controversial given their unique location between the esophagus and the stomach. Debate surrounding the optimal therapy for EGJ adenocarcinoma has often centered around the tumor origin as defined by the Siewert classification system. However, the optimal surgical management should focus on adhering to important surgical principles that will allow for the best outcomes and prognosis regardless of tumor location including resection with appropriate and negative histological margins, adequate lymphadenectomy, minimization of morbidity and mortality, and preservation of quality-of-life. In this article, we provide a discussion of the controversy surrounding EGJ adenocarcinoma within the framework of these concepts. © 2019 The Authors. Annals of Gastroenterological Surgery published by John Wiley & Sons Australia, Ltd on behalf of The Japanese Society of Gastroenterological Surgery
Keywords: adult; clinical article; overall survival; mortality; review; case report; neoadjuvant therapy; positron emission tomography; lymph node dissection; adenocarcinoma; quality of life; morbidity; histology; esophagus resection; minimally invasive surgery; esophageal adenocarcinoma; esophagectomy; chemoradiotherapy; esophageal cancer; abdominal disease; surgical margin; gastroesophageal junction; siewert classification; cancer prognosis; indocyanine green; human; male; priority journal; esophagogastric junction adenocarcinoma
Journal Title: Annals of Gastroenterological Surgery
Volume: 3
Issue: 4
ISSN: 2475-0328
Publisher: Wiley V C H Verlag Gmbh  
Date Published: 2019-07-01
Start Page: 390
End Page: 395
Language: English
DOI: 10.1002/ags3.12268
PROVIDER: scopus
PMCID: PMC6635683
PUBMED: 31346578
DOI/URL:
Notes: Review -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Daniela   Molena
    271 Molena
  2. Tamar B Nobel
    42 Nobel
Related MSK Work