Homeostasis of naive, effector and memory CD8 T cells Journal Article


Authors: Tuma, R. A.; Pamer, E. G.
Article Title: Homeostasis of naive, effector and memory CD8 T cells
Abstract: Homeostatic control of CD8 T cell populations is essential for defense against infectious pathogens. Our understanding of the mechanisms that control naive, effector and memory T cell populations in the intact animal has increased significantly over the last several years. There have been some surprises. For example, peripheral tissues have been found to harbor unexpectedly large numbers of effector memory T cells. Also unexpected was the finding of programmed T cell proliferation following very brief exposure to antigen. These and other recent advances are summarized in the following review.
Keywords: dendritic cells; antigen; proliferation; lymphocytes; mhc class-i; responses; cutting edge; antiviral immunity; bacterial-infection; listeria-monocytogenes infection; exogenous
Journal Title: Current Opinion in Immunology
Volume: 14
Issue: 3
ISSN: 0952-7915
Publisher: Elsevier Inc.  
Date Published: 2002-06-01
Start Page: 348
End Page: 353
Language: English
ACCESSION: WOS:000175202200010
DOI: 10.1016/s0952-7915(02)00338-2
PROVIDER: wos
PUBMED: 11973133
Notes: Review -- Source: Wos
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MSK Authors
  1. Roman Tuma
    5 Tuma
  2. Eric Pamer
    249 Pamer