Structural biology: A molecular propeller Journal Article
| Author: | Patel, D. J. |
| Article Title: | Structural biology: A molecular propeller |
| Abstract: | Telomeres are protein-DNA structures protecting the ends of chromosomes. The crystal structure of a four-stranded stretch of human telomere DNA, bound to K+ ions, has implications for the design of anticancer drugs. |
| Keywords: | antineoplastic agents; antineoplastic agent; proteins; chromosome structure; telomere; cytology; biology; drug design; physiology; dna; tumors; short survey; base sequence; crystal structure; dna structure; models, molecular; crystallography, x-ray; nucleic acid conformation; molecular biology; structure analysis; sodium; repetitive sequences, nucleic acid; nucleotide repeat; chromosomes; potassium; potassium ion; drug products; telomeres; humans; priority journal |
| Journal Title: | Nature |
| Volume: | 417 |
| Issue: | 6891 |
| ISSN: | 0028-0836 |
| Publisher: | Nature Publishing Group |
| Date Published: | 2002-06-20 |
| Start Page: | 807 |
| End Page: | 808 |
| Language: | English |
| DOI: | 10.1038/417807a |
| PUBMED: | 12075337 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Export Date: 14 November 2014 -- Source: Scopus |
