Combined-modality therapy for rectal cancer using irinotecan Journal Article
| Author: | Minsky, B. D. |
| Article Title: | Combined-modality therapy for rectal cancer using irinotecan |
| Abstract: | Preoperative or postoperative pelvic radiation plus concurrent fluorouracil-based chemotherapy is standard adjuvant treatment for patients with T3 and/or N1/2 rectal cancer. Newer chemotherapeutic regimens have been developed for the treatment of patients with metastatic disease. Irinotecan (CPT-11, Camptosar)-based regimens have improved survival in patients with metastatic disease and are being actively investigated in combination with pelvic radiation therapy for patients with rectal cancer. |
| Keywords: | treatment outcome; clinical trial; review; fluorouracil; multimodality cancer therapy; adjuvant therapy; preoperative care; combined modality therapy; radiotherapy, adjuvant; antineoplastic agent; adenocarcinoma; antineoplastic combined chemotherapy protocols; camptothecin; pathology; irinotecan; drug derivative; rectal neoplasms; rectum tumor; clinical trials; humans; human |
| Journal Title: | Oncology (Norwalk) |
| Volume: | 16 |
| Issue: | 5 Suppl. 5 |
| ISSN: | 0890-9091 |
| Publisher: | C M P Medica LLC * The Oncology Group |
| Date Published: | 2002-05-01 |
| Start Page: | 35 |
| End Page: | 38 |
| Language: | English |
| PUBMED: | 12109805 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Export Date: 14 November 2014 -- Source: Scopus |
