Update in the management of endometrial cancer Journal Article


Authors: Levine, D. A.; Hoskins, W. J.
Article Title: Update in the management of endometrial cancer
Abstract: Endometrial cancer is the most common malignancy of the female genital tract and the fourth most common malignancy in women. Standard treatment for early-stage disease involves surgical staging with adjuvant therapy based on pathologic findings. Controversial issues include the role of laparoscopy and the indications for lymph node sampling. Advanced and recurrent disease can be treated with surgery, chemotherapy, or radiation therapy based on the individual pattern of spread and prior treatment regimens. This review will begin by discussing the surgical treatment of early-stage endometrial cancer and the role of adjuvant radiation therapy. The role of surgery and chemotherapy in advanced disease will also be covered. Current experimental protocols and areas of future investigation will be discussed briefly throughout. The standard treatment of endometrial cancer has been the subject of many reviews in the literature. This paper will focus on areas of controversy in the management of endometrial cancer as well as new developments in the treatment of this disease. Recent published reports will be used to highlight changes to traditional practices. The reviewwill be limited to epithelial adenocarcinoma of the endometrium.
Keywords: review; adjuvant therapy; neoadjuvant therapy; cancer staging; methodology; endometrial neoplasms; lymph nodes; neoplasm staging; laparoscopy; adenocarcinoma; risk factors; pathology; risk factor; biopsy; lymph node; endometrium tumor; humans; human; female
Journal Title: The Cancer Journal
Volume: 8 Suppl.1
ISSN: 1528-9117
Publisher: Lippincott Williams & Wilkins  
Date Published: 2002-05-01
Start Page: S31
End Page: S40
Language: English
PUBMED: 12075700
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 14 November 2014 -- Source: Scopus
Citation Impact
MSK Authors
  1. William Hoskins
    255 Hoskins
  2. Douglas A Levine
    380 Levine