High-dose chemotherapy with autologous stem cell rescue for brain tumors Journal Article
| Authors: | Dunkel, I. J.; Finlay, J. L. |
| Article Title: | High-dose chemotherapy with autologous stem cell rescue for brain tumors |
| Abstract: | The use of high-dose chemotherapy with stem cell rescue for malignant brain tumors is reviewed. Promising results have been reported in patients with medulloblastomas, supratentorial PNET's and high-grade astrocytomas. Results thus far have been disappointing for ependymomas and brain stem gliomas. The role of this treatment strategy for other chemotherapy-sensitive tumors such as oligodendrogliomas and central nervous system germ cell tumors has yet to be determined. Copyright © 2002 Elsevier Science Ireland Ltd. |
| Keywords: | adolescent; adult; cancer chemotherapy; child; treatment outcome; child, preschool; disease-free survival; busulfan; review; cancer combination chemotherapy; antineoplastic agents; combined modality therapy; chemotherapy; drug megadose; brain tumor; brain neoplasms; antineoplastic agent; cancer grading; carboplatin; etoposide; cyclophosphamide; melphalan; stem cell transplantation; hematopoietic stem cell transplantation; histology; thiotepa; childhood cancer; medulloblastoma; ependymoma; oligodendroglioma; brain stem tumor; germ cell tumor; astrocytoma; neuroectoderm tumor; transplantation, autologous; clinical trials; autotransplantation; high-grade astrocytoma; humans; male; female; pnet (primitive neuroectodermal tumor) |
| Journal Title: | Critical Reviews in Oncology/Hematology |
| Volume: | 41 |
| Issue: | 2 |
| ISSN: | 1040-8428 |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 2002-02-01 |
| Start Page: | 197 |
| End Page: | 204 |
| Language: | English |
| DOI: | 10.1016/s1040-8428(01)00156-1 |
| PUBMED: | 11856595 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Export Date: 14 November 2014 -- Source: Scopus |
