Predictors of PTSD in mothers of children undergoing bone marrow transplantation: The role of cognitive and social processes Journal Article


Authors: Manne, S.; Duhamel, K.; Nereo, N.; Ostroff, J.; Parsons, S.; Martini, R.; Williams, S.; Mee, L.; Sexson, S.; Wu, L.; Difede, J.; Redd, W. H.
Article Title: Predictors of PTSD in mothers of children undergoing bone marrow transplantation: The role of cognitive and social processes
Abstract: Objective: To investigate the role of cognitive and social processing in posttraumatic stress symptoms and disorder (PTSD) among mothers of children undergoing bone marrow and hematopoietic stem-cell transplantation (BMT/SCT). Method: Questionnaires assessing emotional distress, BMT-related fears, and negative responses of family and friends were completed by 90 mothers at the time of the BMT infusion and 3 and 6 months post-BMT. PTSD symptoms were measured 6 months post-BMT by both paper-and-pencil and structured interview methods. Results: Emotional distress, BMT-related fears, and negative responses of family and friends assessed at the time of BMT hospitalization were predictive of later PTSD symptoms. None of these variables prospectively predicted a PTSD diagnosis as measured by the structured interview. Conclusions: Higher levels of general psychological distress, cognitive interpretations of the threat of the BMT for the child's future functioning, and negative responses of family and friends may place mothers at risk for post-BMT posttraumatic stress symptomatology.
Keywords: adult; child; controlled study; middle aged; major clinical study; follow-up studies; prospective studies; risk factors; stem cell transplantation; hematopoietic stem cell transplantation; prediction; questionnaires; questionnaire; social support; cognition; posttraumatic stress disorder; attitude; social aspect; bone marrow transplantation; awareness; mother; mothers; family; emotional stress; psychological distress; stress disorders, post-traumatic; pediatric bone marrow transplantation; friends; humans; human; female; article
Journal Title: Journal of Pediatric Psychology
Volume: 27
Issue: 7
ISSN: 0146-8693
Publisher: Oxford University Press  
Date Published: 2002-10-01
Start Page: 607
End Page: 617
Language: English
DOI: 10.1093/jpepsy/27.7.607
PUBMED: 12228332
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 14 November 2014 -- Source: Scopus
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  1. Jamie S Ostroff
    344 Ostroff