Translocation of Broca's area to the contralateral hemisphere as the result of the growth of a left inferior frontal glioma Journal Article


Authors: Holodny, A. I.; Schulder, M.; Ybasco, A.; Liu, W. C.
Article Title: Translocation of Broca's area to the contralateral hemisphere as the result of the growth of a left inferior frontal glioma
Abstract: We report a case of a patient with a left inferior frontal glioma in whom language functional magnetic resonance imaging (fMRI) paradigms produced activation of Broca's area on the right and Wernicke's area on the left. We propose that tumor invasion of the left frontal operculum led to cortical reorganization and interhemispheric transfer of Broca's area. This case emphasizes the importance of preoperative fMRI in assessing the location of eloquent cortices adjacent to a tumor and in guiding neurosurgical decision-making.
Keywords: adult; cancer chemotherapy; cancer surgery; clinical feature; case report; treatment planning; cancer radiotherapy; nuclear magnetic resonance imaging; glioma; neurosurgery; brain neoplasms; magnetic resonance imaging; antineoplastic agent; preoperative evaluation; medical decision making; image analysis; tumor biopsy; diagnostic imaging; postoperative complications; cancer invasion; symptom; image enhancement; temporal lobe; contrast enhancement; language; frontal lobe; functional laterality; gadolinium pentetate; brain biopsy; decision making; astrocytoma; brain hernia; functional mri; stereotaxic surgery; neurosurgical procedures; diagonal band of broca; sensory cortex; humans; human; male; priority journal; article; broca's area
Journal Title: Journal of Computer Assisted Tomography
Volume: 26
Issue: 6
ISSN: 0363-8715
Publisher: Lippincott Williams & Wilkins  
Date Published: 2002-11-01
Start Page: 941
End Page: 943
Language: English
DOI: 10.1097/00004728-200211000-00014
PUBMED: 12488739
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 14 November 2014 -- Source: Scopus
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  1. Andrei Holodny
    206 Holodny