Author: | Hohl, T. M. |
Article Title: | Overview of vertebrate animal models of fungal infection |
Abstract: | Fungi represent emerging infectious threats to human populations worldwide. Mice and other laboratory animals have proved invaluable in modeling clinical syndromes associated with superficial and life-threatening invasive mycoses. This review outlines salient features of common vertebrate animal model systems to study fungal pathogenesis, host antifungal immune responses, and antifungal compounds. |
Keywords: | pathogenesis; review; nonhuman; mouse; animal; metabolism; animals; animal model; antifungal agent; pathology; experimental animal; disease model; immunology; immune response; yeast; disease models, animal; vertebrate; mycosis; fungus; fungal strain; systemic mycosis; mycoses; humans; human; apparent life threatening event |
Journal Title: | Journal of Immunological Methods |
Volume: | 410 |
ISSN: | 0022-1759 |
Publisher: | Elsevier Science, Inc. |
Date Published: | 2014-08-01 |
Start Page: | 100 |
End Page: | 112 |
Language: | English |
DOI: | 10.1016/j.jim.2014.03.022 |
PUBMED: | 24709390 |
PROVIDER: | scopus |
PMCID: | PMC4163114 |
DOI/URL: | |
Notes: | Export Date: 1 December 2014 -- Source: Scopus |