Novel imaging provides new insights into mechanisms of oxygen transport in tumors Journal Article


Authors: Hardee, M. E.; Dewhirst, M. W.; Agarwal, N.; Sorg, B. S.
Article Title: Novel imaging provides new insights into mechanisms of oxygen transport in tumors
Abstract: Hypoxia is a common feature of solid tumors, and abnormal tumor oxygen transport is a key factor in the imbalance between tumor oxygen supply and demand. Novel advanced imaging techniques can enable new insights into the complexities of tumor oxygen transport and hypoxia that were not previously known or fully appreciated. In this paper, we document new insights into tumor oxygen transport enabled by spectral imaging of microvascular hemoglobin saturation. © 2009 Bentham Science Publishers Ltd.
Keywords: review; nonhuman; solid tumor; neoplasms; animals; oxygen; molecular imaging; diagnostic imaging; cell transformation, neoplastic; hypoxia; image quality; cell hypoxia; oxygen transport; spectroscopy; blood oxygenation; oxyhemoglobin; image display; imaging and display; microvascularization; oxygen saturation; spectral imaging; hemoglobins
Journal Title: Current Molecular Medicine
Volume: 9
Issue: 4
ISSN: 1566-5240
Publisher: Bentham Science Publishers  
Date Published: 2009-05-01
Start Page: 435
End Page: 441
Language: English
DOI: 10.2174/156652409788167122
PUBMED: 19519401
PROVIDER: scopus
PMCID: PMC2841217
DOI/URL:
Notes: --- - "Cited By (since 1996): 2" - "Export Date: 30 November 2010" - "CODEN: CMMUB" - "Source: Scopus"
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  1. Matthew Emery Hardee
    1 Hardee