Management of recurrence and follow-up strategies for patients with seminoma and selected high-risk groups Journal Article
| Authors: | Patel, M. I.; Motzer, R. J.; Sheinfeld, J. |
| Article Title: | Management of recurrence and follow-up strategies for patients with seminoma and selected high-risk groups |
| Abstract: | Seminoma is characterized by high sensitivity to both radiation and chemotherapy. Localized recurrences in the retroperitoneum after surveillance for stage I can be treated with radiotherapy; however, multiple or large bulky retroperitoneal recurrences or systemic metastasis requires cisplatin-based chemotherapy. Salvage chemotherapy for those who recur after initial CR to induction chemotherapy is based on ifosfamide- and cisplatin-containing regimens. Incomplete response or failure after induction chemotherapy requires high-dose chemotherapy and stem cell rescue. Patients with seminoma need long-term follow-up because of the possibility of late recurrence and the risk of a second primary tumor. |
| Keywords: | cancer chemotherapy; cancer survival; treatment outcome; cancer surgery; survival rate; clinical trial; disease course; histopathology; paresthesia; review; cancer localization; cancer recurrence; salvage therapy; cisplatin; ascites; cancer combination chemotherapy; hypertension; patient selection; bone metastasis; cancer patient; cancer radiotherapy; radiation dose; cancer staging; neurotoxicity; nuclear magnetic resonance imaging; positron emission tomography; follow up; lymph node metastasis; antineoplastic agent; neoplasm staging; carboplatin; metastasis; computer assisted tomography; liver toxicity; lung toxicity; nephrotoxicity; tumor volume; etoposide; recurrence; cyclophosphamide; clinical protocol; kidney failure; stem cell transplantation; radiation injury; bladder tumor; ifosfamide; vinblastine; acute lymphoblastic leukemia; high risk patient; testis disease; hyperuricemia; hypomagnesemia; liver metastasis; lung metastasis; cryopreservation; acute leukemia; cerebrovascular disease; peripheral vascular disease; spinal cord compression; surgical infection; brain metastasis; testicular neoplasms; dactinomycin; bleomycin; postoperative infection; thyroid cancer; vinca alkaloid; cancer epidemiology; inguinal lymph node; orchiectomy; hypercholesterolemia; germ cell tumor; neurologic disease; seminoma; meta analysis; autonomic neuropathy; retroperitoneal cancer; small intestine obstruction; raynaud phenomenon; radiation carcinogenesis; intractable pain; mediastinum metastasis; male infertility; substance abuse; cryptorchism; autotransplantation; testis atrophy; acute nonlymphocytic leukemia; small intestine tumor; connective tissue tumor; low fat diet; myelodysplasia; nerve conduction; testis biopsy; artificial insemination; blood vessel occlusion; humans; human; male; priority journal; testicular microlithiasis |
| Journal Title: | Urologic Clinics of North America |
| Volume: | 30 |
| Issue: | 4 |
| ISSN: | 0094-0143 |
| Publisher: | W.B. Saunders Co-Elsevier Inc. |
| Date Published: | 2003-11-01 |
| Start Page: | 803 |
| End Page: | 817 |
| Language: | English |
| DOI: | 10.1016/s0094-0143(03)00063-6 |
| PUBMED: | 14680316 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Export Date: 25 September 2014 -- Source: Scopus |
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