Epiphyseal osteoblastoma of tibia with xanthomatous stromal reaction Journal Article
| Authors: | Zhang, X.; Bukata, S. V.; Healey, J. H.; Huvos, A. G. |
| Article Title: | Epiphyseal osteoblastoma of tibia with xanthomatous stromal reaction |
| Abstract: | Osteoblastoma occurring in long bones has a distinctive predilection for the metaphysis and the diaphysis. Epiphyseal location is rare. Although variation in histologic patterns is a well-known feature of this tumor, xanthomatous stromal reaction has not yet been described. We report a case of a 34-year-old man who developed an osteoblastoma primarily located in the epiphysis of his left tibia with extension into the metaphysis. The striking histologic features included a prominent xanthoma-like stroma consisting of foamy histiocytes in addition to focal areas with classical configuration of an osteoblastoma. The significance of this finding is discussed. |
| Keywords: | adult; human tissue; bone neoplasms; disease-free survival; bone tumor; case report; histology; histiocyte; stromal cells; tibia; epiphysis; osteoblastoma; xanthomatosis; humans; human; male; priority journal; article; epiphyseal osteoblastoma; foamy histiocytes; xanthoma-like stroma; epiphyses |
| Journal Title: | Annals of Diagnostic Pathology |
| Volume: | 7 |
| Issue: | 6 |
| ISSN: | 1092-9134 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2003-12-01 |
| Start Page: | 360 |
| End Page: | 364 |
| Language: | English |
| DOI: | 10.1016/j.anndiagpath.2003.09.008 |
| PUBMED: | 15018119 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Export Date: 12 September 2014 -- Source: Scopus |
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