Osteoid osteoma and osteoblastoma: Current concepts and recent advances Journal Article


Authors: Healey, J. H.; Ghelman, B.
Article Title: Osteoid osteoma and osteoblastoma: Current concepts and recent advances
Abstract: Osteoid osteomas are common lesions, constituting one-eight of the benign bone tumors. Their size (less than 1.5 cm) and characteristic radiographic and clinical presentation are usually diagnostic. Response to salicylates is quite variable and not a reliable sign. Extremely high levels of prostaglandin metabolites have been found in osteoid osteomas and may explain the inflammatory features of the lesions. Preoperative localization with computed tomography (CT) scans and intraoperative confirmation of location and resection with radioscintingraphy have dramatically reduced the recurrence rate in the last 26 patients. Complete excision, even if accomplished by intralesional technique, is successful in eradicating the tumor. Osteoblastomas constitute 1% of bone tumors. Although their histology differs minimally from osteoid osteomas, they achieve a larger size and behave more aggressively. Commonly occurring in the spine, they require careful anatomic delineation with CT scans and myelography. Complete excision eliminates the lesion.
Keywords: major clinical study; review; computer assisted tomography; diagnosis; bone; therapy; spine tumor; computer analysis; osteoblastoma; myelography; osteoid osteoma; human; priority journal
Journal Title: Clinical Orthopaedics and Related Research
Volume: 204
ISSN: 0009-921X
Publisher: Springer  
Date Published: 1986-03-01
Start Page: 76
End Page: 85
Language: English
DOI: 10.1097/00003086-198603000-00008
PUBMED: 3956019
PROVIDER: scopus
DOI/URL:
Notes: Article -- Export Date: 18 August 2021 -- Source: Scopus
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  1. John H Healey
    547 Healey
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