Bone marrow oedema associated with benign and malignant bone tumours Journal Article


Authors: James, S. L. J.; Panicek, D. M.; Davies, A. M.
Article Title: Bone marrow oedema associated with benign and malignant bone tumours
Abstract: Bone marrow oedema is associated with a wide variety of pathological processes including both benign and malignant bone tumours. This imaging finding in relation to intraosseous tumours can aid in providing a more focused differential diagnosis. In this review, we will discuss the MR imaging of bone marrow oedema surrounding intraosseous neoplasms. The different pulse sequences used in differentiating underlying tumour from surrounding oedema are discussed along with the role of dynamic contrast enhanced MRI. Benign lesions commonly associated with bone marrow oedema include osteoid osteoma, osteoblastoma, chondroblastoma and Langerhan's cell histiocytosis. Metastases and malignant primary bone tumours such as osteosarcoma, Ewing's sarcoma and chondrosarcoma may also be surrounded by bone marrow oedema. The imaging findings of these conditions are reviewed and illustrated. Finally, the importance of bone marrow oedema in assessment of post chemotherapeutic response is addressed. © 2008 Elsevier Ireland Ltd. All rights reserved.
Keywords: osteosarcoma; bone neoplasms; bone tumor; chemotherapy; nuclear magnetic resonance imaging; magnetic resonance imaging; edema; computer assisted tomography; diagnosis, differential; pathology; diagnostic imaging; ewing sarcoma; tumors; diagnosis; bone; chondrosarcoma; diseases; mri; bone marrow disease; langerhans cell; histiocytosis x; chondroblastoma; osteoblastoma; oedema; bone marrow oedema; langerhan's cell histiocytosis; pulse sequences; osteoid osteoma; thermocoagulation; bone marrow diseases
Journal Title: European Journal of Radiology
Volume: 67
Issue: 1
ISSN: 0720-048X
Publisher: Elsevier B.V  
Date Published: 2008-07-01
Start Page: 11
End Page: 21
Language: English
DOI: 10.1016/j.ejrad.2008.01.052
PUBMED: 18358660
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 10" - "Export Date: 17 November 2011" - "CODEN: EJRAD" - "Source: Scopus"
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  1. David M Panicek
    135 Panicek