Magnetic resonance imaging of bone marrow in oncology, Part 1 Journal Article


Authors: Hwang, S.; Panicek, D. M.
Article Title: Magnetic resonance imaging of bone marrow in oncology, Part 1
Abstract: Magnetic resonance imaging plays an integral role in the detection and characterization of marrow lesions, planning for biopsy or surgery, and post-treatment follow-up. To evaluate findings in bone marrow on MR imaging, it is essential to understand the normal composition and distribution of bone marrow and the changes in marrow that occur with age, as well as the basis for the MR signals from marrow and the factors that affect those signals. The normal distribution of red and yellow marrow in the skeleton changes with age in a predictable sequence. Important factors that affect MR signals and allow detection of marrow lesions include alterations in fat-water distribution, destruction of bony trabeculae, and contrast enhancement. This two-part article reviews and illustrates these issues, with an emphasis on the practical application of MR imaging to facilitate differentiation of normal marrow, tumor, and treatment-related marrow changes in oncology patients. © ISS 2007.
Keywords: review; treatment planning; cancer patient; nuclear magnetic resonance imaging; follow up; magnetic resonance imaging; bone marrow; age; sarcoma; image enhancement; bone marrow biopsy; contrast enhancement; medical oncology; water; metastases; tumor; tissue injury; signal processing; signal detection; fat; bone marrow neoplasms; marrow; skeleton; treatment effects; trabecular bone
Journal Title: Skeletal Radiology
Volume: 36
Issue: 10
ISSN: 0364-2348
Publisher: Springer  
Date Published: 2007-10-01
Start Page: 913
End Page: 920
Language: English
DOI: 10.1007/s00256-007-0309-3
PUBMED: 17492443
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 13" - "Export Date: 17 November 2011" - "CODEN: SKRAD" - "Source: Scopus"
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  1. David M Panicek
    134 Panicek
  2. Sinchun Hwang
    96 Hwang