Elevated β-hCG associated with aggressive osteoblastoma Journal Article
| Authors: | Morris, C. D.; Hameed, M. R.; Agaram, N. P.; Hwang, S. |
| Article Title: | Elevated β-hCG associated with aggressive osteoblastoma |
| Abstract: | We present a unique case of an aggressive scapular osteoblastoma that produced β-hCG as a paraneoplastic manifestation in a 20-year-old woman. Serum β-hCG was found to be elevated during presurgical workup and consequently delayed surgical resection of the increasingly painful tumor because of suspected pregnancy. The paraneoplastic production of β-hCG was later proven by positive immunohistochemical stain of β-hCG in a curettage specimen and normalization of β-hCG levels after surgical resection of the aggressive osteoblastoma. Production of beta-human chorionic gonadotropin (β-hCG) has been reported in several carcinomas and sarcomas but, to our knowledge, it has not been reported in osteoblastoma in the English-language literature. © 2017, ISS. |
| Keywords: | β-hcg; beta-human chorionic gonadotropin; osteoblastoma, paraneoplastic |
| Journal Title: | Skeletal Radiology |
| Volume: | 46 |
| Issue: | 9 |
| ISSN: | 0364-2348 |
| Publisher: | Springer |
| Date Published: | 2017-09-01 |
| Start Page: | 1187 |
| End Page: | 1192 |
| Language: | English |
| DOI: | 10.1007/s00256-017-2647-0 |
| PROVIDER: | scopus |
| PUBMED: | 28396962 |
| DOI/URL: | |
| Notes: | Article -- Export Date: 1 August 2017 -- Source: Scopus |
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