Respiratory artefact causing malpositioning of liver dome lesion in right lower lung Journal Article


Authors: Sarikaya, I.; Yeung, H. W. D.; Erdi, Y.; Larson, S. M.
Article Title: Respiratory artefact causing malpositioning of liver dome lesion in right lower lung
Abstract: The new combined positron emission (PET)/computed tomographic (CT) scanners have many advantages over PET scanners alone. However, physicians must be aware of the potential artefacts observed in PET/CT scanners. A body PET/CT was performed on an 81-year-old man with colorectal cancer. The CT-based, attenuation-corrected PET image showed a right lower lung lesion. However, there was no lung lesion on the transmission CT image. Nonattenuation-corrected PET, and rod source-based, attenuation-corrected PET images demonstrated focal uptake in the dome of the liver. Dedicated CT with intravenous contrast confirmed that the lesion was in the liver dome and not in the right lower lung. The liver lesion was misplaced to the right lower lung in the CT-based, attenuation-corrected PET image because of a respiratory artefact. To overcome this respiration artefact the authors suggest a routine review of the nonattenuation-corrected PET images, particularly when evaluating liver dome and lower lung lesions.
Keywords: aged; aged, 80 and over; cancer surgery; case report; fluorouracil; liver neoplasms; cancer adjuvant therapy; positron emission tomography; recurrent cancer; radiopharmaceuticals; colorectal cancer; metastasis; computer assisted tomography; lung disease; carcinoembryonic antigen; tomography, x-ray computed; liver; diagnostic agent; minimal residual disease; liver tumor; fluorodeoxyglucose f 18; computer assisted emission tomography; hypermetabolism; fluorodeoxyglucose f18; lung; radiopharmaceutical agent; scintiscanning; liver disease; radiography; artifact; image processing, computer-assisted; image processing; respiration; pet; ct; artifacts; tomography, emission-computed; breathing; levamisole; germanium; humans; human; male; female; article; respiratory artefact
Journal Title: Clinical Nuclear Medicine
Volume: 28
Issue: 11
ISSN: 0363-9762
Publisher: Lippincott Williams & Wilkins  
Date Published: 2003-11-01
Start Page: 943
End Page: 944
Language: English
DOI: 10.1097/01.rlu.0000093095.28642.2b
PUBMED: 14578720
PROVIDER: scopus
DOI/URL:
Notes: Export Date: 12 September 2014 -- Source: Scopus
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  1. Henry W D Yeung
    126 Yeung
  2. Yusuf E Erdi
    118 Erdi
  3. Steven M Larson
    959 Larson