Treatment of recurrent of papillary thyroid carcinoma in children and adolescents Journal Article
| Authors: | Powers, P. A.; Dinauer, C. A.; Tuttle, R. M.; Francis, G. L. |
| Article Title: | Treatment of recurrent of papillary thyroid carcinoma in children and adolescents |
| Abstract: | Mortality for children with papillary thyroid carcinoma (PTC) is low (≤10%), but recurrence is frequent (20%). In adults, recurrent PTC has a poor prognosis (50% remission) and a high mortality (16-63%). We hypothesized that treatment of recurrent PTC would be more effective in children than in adults. We reviewed the clinical course of 42 children with PTC in remission. Seven (7/42, 17%) recurred and records were available for six. All six received RAI (median = 130 mCi), and one had a cervical node removed. Five of the six (83%) achieved remission (median duration 67 mo, range 10-99 mo), one had a second recurrence and a third remission, and one patient (17%) had persistent disease. There were no deaths. In conclusion, although we had only one child less than 10 years of age in our study, these and previous data suggest that treatment of recurrent PTC in children is generally effective. |
| Keywords: | adolescent; cancer survival; child; clinical article; controlled study; treatment outcome; retrospective studies; disease course; mortality; cancer risk; cancer staging; recurrent cancer; follow-up studies; cancer incidence; cancer grading; computer assisted tomography; carcinoma, papillary; recurrence; cancer mortality; childhood cancer; cancer regression; iodine 131; radioactive iodine; carcinoma; thyroidectomy; outcome; thyroid neoplasms; cancer classification; thyroglobulin; radioimmunotherapy; children; thyroid papillary carcinoma; thyroid; papillary; humans; prognosis; human; male; female; article |
| Journal Title: | Journal of Pediatric Endocrinology and Metabolism |
| Volume: | 16 |
| Issue: | 7 |
| ISSN: | 0334-018X |
| Publisher: | De Gruyter |
| Date Published: | 2003-09-01 |
| Start Page: | 1033 |
| End Page: | 1040 |
| Language: | English |
| PUBMED: | 14513881 |
| PROVIDER: | scopus |
| DOI: | 10.1515/JPEM.2003.16.7.1033 |
| DOI/URL: | |
| Notes: | Export Date: 12 September 2014 -- Source: Scopus |
