Authors: | Khalaj, M.; Park, C. Y. |
Article Title: | Notch one up to stroma: Endothelial notch prevents inflammation and myeloproliferation |
Abstract: | In this issue of Cell Stem Cell, Wang et al. (2014) describe a signaling axis present in bone marrow stromal cells that suppresses inflammation and myeloid expansions. Loss of endothelial Notch signaling leads to deregulation of miR-155 expression, activation of NF-kB, and increased proinflammatory cytokine production, which promotes a myeloproliferative phenotype. © 2014 Elsevier Inc. |
Journal Title: | Cell Stem Cell |
Volume: | 15 |
Issue: | 1 |
ISSN: | 1934-5909 |
Publisher: | Cell Press |
Date Published: | 2014-07-03 |
Start Page: | 1 |
End Page: | 2 |
Language: | English |
DOI: | 10.1016/j.stem.2014.06.010 |
PROVIDER: | scopus |
PUBMED: | 24996160 |
DOI/URL: | |
Notes: | Export Date: 1 August 2014 -- Source: Scopus |