Modifying histones and initiating meiotic recombination: New answers to an old question Journal Article
| Authors: | Maleki, S.; Keeney, S. |
| Article Title: | Modifying histones and initiating meiotic recombination: New answers to an old question |
| Abstract: | It is well documented that the formation of the DNA double-strand breaks (DSBs) that initiate meiotic recombination is influenced by chromatin and larger scale chromosome organization, but the molecular nature of this influence has remained elusive. Several recent studies, including Reddy and Villeneuve (2004)(this issue of Cell), shed light on this issue by revealing roles for posttranslational histone modifications in promoting DSB formation. |
| Keywords: | gene mutation; nonhuman; note; animal; meiosis; metabolism; animals; dna damage; biological model; models, biological; molecular dynamics; drosophila; physiology; dna strand breakage; chemistry; dna; genetic recombination; protein processing; protein processing, post-translational; saccharomyces cerevisiae; histone; chromatin; recombination, genetic; short survey; caenorhabditis elegans; chromosome analysis; histones; caenorhabditis; saccharomyces; priority journal |
| Journal Title: | Cell |
| Volume: | 118 |
| Issue: | 4 |
| ISSN: | 0092-8674 |
| Publisher: | Cell Press |
| Date Published: | 2004-08-20 |
| Start Page: | 404 |
| End Page: | 406 |
| Language: | English |
| DOI: | 10.1016/j.cell.2004.08.008 |
| PUBMED: | 15315752 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | Cited By (since 1996):9 -- Export Date: 16 June 2014 -- CODEN: CELLB -- Source: Scopus |
