The Framingham school nevus study: A pilot study Journal Article

Authors: Oliveria, S. A.; Geller, A. C.; Dusza, S. W.; Marghoob, A. A.; Sachs, D.; Weinstock, M. A.; Buckminster, M.; Halpern, A. C.
Article Title: The Framingham school nevus study: A pilot study
Abstract: Objectives: To (1) describe nevus patterns using digital photography and dermoscopy; (2) evaluate the relationship between host and environmental factors and prevalence of nevi in schoolchildren; and (3) demonstrate the feasibility of conducting a longitudinal study. Design: Cross-sectional survey and 1-year prospective follow-up study. Participants: Students from 2 classrooms, grades 6 and 7, in the Framingham, Mass, school system (N = 52). Main Outcome Measures: A survey was completed by students and 1 of their parents that included questions on demographic and phenotypic characteristics, family history of skin cancer, and sun exposure and protection practices. An examination of nevi on the back was performed that included digital photography and digital dermoscopy. Follow-up child and parent surveys and examinations were conducted at 1-year follow-up. Results: At baseline, the median number of back nevi was 15 (mean [SD], 21.9 [15.3]). Older age, male sex, fair skin, belief that a tan is healthier, tendency to burn, and sporadic use of sunscreen were positively associated with mole count, although age was the only statistically significant factor. Predominant dermoscopic patterns for the index nevus were as follows: 38% globular, 14% reticulated, 38% structureless, and 10% combinations of the above patterns with no predominant characteristic. The overall participation rate from baseline to follow-up was 81% (42/ 52) for the skin examination process. At the 1-year follow-up examination, new nevi were identified in 36% of students (n = 15), while 9.6% of baseline index nevi had changes in the dermoscopic pattern. Dominant dermoscopic pattern was related to nevus size: smaller nevi tended to be structureless, while larger nevi were of mixed pattern. Conclusion: This study supports the feasibility and utility of digital photography and dermoscopy for the longitudinal study of nevus evolution in early adolescence.
Keywords: adolescent; adult; child; school child; major clinical study; review; microscopy; follow up; prospective studies; melanoma; nevus; prevalence; risk factors; cancer screening; age factors; epiluminescence microscopy; longitudinal studies; pilot projects; cross-sectional studies; medical photography; sex factors; photography; longitudinal study; massachusetts; humans; human; male; female; priority journal
Journal Title: Archives of Dermatology
Volume: 140
Issue: 5
ISSN: 0003-987X
Publisher: American Medical Association  
Date Published: 2004-05-01
Start Page: 545
End Page: 551
Language: English
DOI: 10.1001/archderm.140.5.545
PROVIDER: scopus
PUBMED: 15148098
Notes: Arch. Dermatol. -- Cited By (since 1996):35 -- Export Date: 16 June 2014 -- CODEN: ARDEA -- Source: Scopus
Citation Impact
MSK Authors
  1. Allan C Halpern
    385 Halpern
  2. Stephen Dusza
    255 Dusza
  3. Ashfaq A Marghoob
    507 Marghoob
  4. Dana L Sachs
    23 Sachs