Clinical and dermoscopic changes in common melanocytic nevi in school children: The framingham school nevus study Journal Article
| Authors: | LaVigne, E. A.; Oliveria, S. A.; Dusza, S. W.; Geller, A. C.; Halpern, A. C.; Marghoob, A. A. |
| Article Title: | Clinical and dermoscopic changes in common melanocytic nevi in school children: The framingham school nevus study |
| Abstract: | Background: Nevi are potential precursors of malignant melanoma and are important risk factors for the development of the disease. Childhood may be a critical time for the formation and evolution of nevi. Objectives: To document the development of new nevi and to document the clinical and dermoscopic changes in index nevi in school children during a 1-year follow-up. Methods: Digital photographs and dermoscopic images of the back of subjects were compared at baseline and 1-year follow-up to assess changes in nevi counts and in clinical and dermoscopic features of index nevi. Results: Overall participation rate was 81% (42/52). 56.4% of study participants were found to have an increased number of nevi at 1-year follow-up. All nevi were small and clinically insignificant. Fifty percent of study participants were found to have dermoscopic changes in their index nevi at 1-year follow-up. Eighty-five percent of these changes were classified as subtle and 15.0% as obvious. Conclusions: A significant portion of students developed new nevi over the course of 1 year. Most index nevi remained stable in pattern and structure. Benign dermoscopic changes occurred in 50.0% of index nevi. However, none of the dermoscopically changed nevi revealed any major changes and the overall nevus pattern remained unchanged. The relevance of these changes is uncertain and further follow-up may elucidate their significance. Copyright © 2005 S. Karger AG. |
| Keywords: | adolescent; clinical article; controlled study; school child; clinical feature; microscopy; follow up; follow-up studies; melanoma; dermoscopy; skin neoplasms; risk factor; epiluminescence microscopy; risk assessment; disease severity; melanocytic nevus; nevus, pigmented; pilot projects; disease progression; childhood; photography; clinical examination; common melanocytic nevi |
| Journal Title: | Dermatology |
| Volume: | 211 |
| Issue: | 3 |
| ISSN: | 1018-8665 |
| Publisher: | S. Karger AG |
| Date Published: | 2005-01-01 |
| Start Page: | 234 |
| End Page: | 239 |
| Language: | English |
| DOI: | 10.1159/000087017 |
| PUBMED: | 16205068 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Cited By (since 1996): 10" - "Export Date: 24 October 2012" - "CODEN: DERAE" - "Source: Scopus" |
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