Immune responses to Listeria monocytogenes Journal Article
| Author: | Pamer, E. G. |
| Article Title: | Immune responses to Listeria monocytogenes |
| Abstract: | Listeria monocytogenes is a Gram-positive bacterium that is often used to study the mammalian immune response to infection because it is easy to culture, is relatively safe to work with and causes a highly predictable infection in laboratory mice. The broad application of this mouse model has resulted in a torrent of studies characterizing the contributions of different cytokines, receptors, adaptors and effector molecules to resistance against infection with Listeria monocytogenes. These studies, which are yielding one of the most comprehensive pictures of the 'battle' between host and microorganism, are reviewed here. |
| Keywords: | signal transduction; protein expression; unclassified drug; pathogenesis; review; nonhuman; protein function; lymphocyte proliferation; t-lymphocytes; animals; mice; cell protein; inflammation; gene function; bacterial virulence; experimental animal; lymphocyte activation; cellular immunity; immune response; gamma interferon; antigen specificity; gene control; cytokine production; dna vaccine; cd4 antigen; bacterial genome; disease models, animal; memory cell; bacterium culture; cell invasion; t lymphocyte subpopulation; myeloid differentiation factor 88; toll like receptor; chemokine receptor ccr2; infection sensitivity; listeriosis; listeria monocytogenes; listeria infections; live vaccine; gene expression regulation, bacterial; major histocompatibility antigen class 1; major histocompatibility complex restriction; immunization; inactivated vaccine; infection resistance; macrophage activation; bacterial vaccine; immunity, natural; virulence factor; mucosal immunity; humans; human; priority journal; interleukin 1 receptor associated kinase; listeria monocytogenes vaccine; protein llo |
| Journal Title: | Nature Reviews Immunology |
| Volume: | 4 |
| Issue: | 10 |
| ISSN: | 1474-1733 |
| Publisher: | Nature Publishing Group |
| Date Published: | 2004-10-01 |
| Start Page: | 812 |
| End Page: | 823 |
| Language: | English |
| DOI: | 10.1038/nri1461 |
| PROVIDER: | scopus |
| PUBMED: | 15459672 |
| DOI/URL: | |
| Notes: | Nat. Rev. Immunol. -- Cited By (since 1996):384 -- Export Date: 16 June 2014 -- CODEN: NRIAB -- Source: Scopus |
