Levofloxacin-induced radiation recall dermatitis: A case report and a review of the literature Journal Article
| Authors: | Wernicke, A. G.; Swistel, A.; Parashar, B.; Myskowski, P. |
| Article Title: | Levofloxacin-induced radiation recall dermatitis: A case report and a review of the literature |
| Abstract: | Radiation recall dermatitis (RRD) is a rare phenomenon. There are a few reports in the literature reporting RRD triggered by quinolones administration after external beam radiation therapy (EBRT). We present an unusual case of RRD induced by levofloxacin 7 months after completion of EBRT. A 56-year-old Caucasian female was treated with EBRT for stage I carcinoma of the right breast with whole breast irradiation followed by the boost to the tumor bed to a total dose of 6080 cGy. Seven months post completion of EBRT, levofloxacin was administered for an upper respiratory tract infection. On day 8 of levofloxacin, the patient developed a blistering RRD in the skin overlying the area of previous radiation portals. Discontinuation of the RRD-inducing antibiotic and appropriate therapy led to the resolution of the condition. We review literature emphasizing this quinolone antibiotic as a causative of RRD. |
| Keywords: | adult; middle aged; case report; drug withdrawal; radiation dose; radiotherapy, adjuvant; sentinel lymph node biopsy; breast neoplasms; pruritus; anti-bacterial agents; breast carcinoma; partial mastectomy; erythema; radiation therapy; external beam radiotherapy; drug substitution; levofloxacin; radiation dermatitis; ofloxacin; upper respiratory tract infection; carcinoma, lobular; clobetasol; quinolone; clindamycin; radiodermatitis; blister; famciclovir; antibiotic; papulovesicular rash; radiation recall dermatitis; respiratory tract infections |
| Journal Title: | Clinical Breast Cancer |
| Volume: | 10 |
| Issue: | 10 |
| ISSN: | 1526-8209 |
| Publisher: | Elsevier Inc. |
| Date Published: | 2010-10-01 |
| Start Page: | 404 |
| End Page: | 406 |
| Language: | English |
| DOI: | 10.3816/CBC.2010.n.054 |
| PUBMED: | 20920986 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Export Date: 20 April 2011" - "CODEN: CBCLB" - "Source: Scopus" |
