External-beam radiotherapy for differentiated thyroid cancer locoregional control: A statement of the American Head and Neck Society Journal Article


Authors: Kiess, A. P.; Agrawal, N.; Brierley, J. D.; Duvvuri, U.; Ferris, R. L.; Genden, E.; Wong, R. J.; Tuttle, R. M.; Lee, N. Y.; Randolph, G. W.
Article Title: External-beam radiotherapy for differentiated thyroid cancer locoregional control: A statement of the American Head and Neck Society
Abstract: The use of external-beam radiotherapy (EBRT) in differentiated thyroid cancer (DTC) is debated because of a lack of prospective clinical data, but recent retrospective studies have reported benefits in selected patients. The Endocrine Surgery Committee of the American Head and Neck Society provides 4 recommendations regarding EBRT for locoregional control in DTC, based on review of literature and expert opinion of the authors. (1) EBRT is recommended for patients with gross residual or unresectable locoregional disease, except for patients <45 years old with limited gross disease that is radioactive iodine (RAI)-avid. (2) EBRT should not be routinely used as adjuvant therapy after complete resection of gross disease. (3) After complete resection, EBRT may be considered in select patients >45 years old with high likelihood of microscopic residual disease and low likelihood of responding to RAI. (4) Cervical lymph node involvement alone should not be an indication for adjuvant EBRT. © 2015 Wiley Periodicals, Inc.
Keywords: radiation; radiotherapy; thyroid cancer; papillary; follicular
Journal Title: Head & Neck
Volume: 38
Issue: 4
ISSN: 1043-3074
Publisher: John Wiley & Sons, Inc.  
Date Published: 2016-04-01
Start Page: 493
End Page: 498
Language: English
DOI: 10.1002/hed.24357
PROVIDER: scopus
PUBMED: 26716601
PMCID: PMC4975923
DOI/URL:
Notes: Review -- Export Date: 2 May 2016 -- Source: Scopus
Altmetric
Citation Impact
BMJ Impact Analytics
MSK Authors
  1. Robert M Tuttle
    483 Tuttle
  2. Nancy Y. Lee
    876 Lee
  3. Richard J Wong
    415 Wong