Multiple subclinical syringomatous proliferations encountered during Mohs surgery for basal cell carcinoma Journal Article


Authors: Amin, S. P.; Herman, A. R.; Busam, K. J.; Sachs, D. L.; Nehal, K. S.
Article Title: Multiple subclinical syringomatous proliferations encountered during Mohs surgery for basal cell carcinoma
Abstract: BACKGROUND. Examination of Mohs surgery frozen sections may lead to discovery of incidental benign neoplasms such as syringomas. OBJECTIVE. An unusual occurrence of numerous subclinical syringomatous proliferations discovered during Mohs surgery for a basal cell carcinoma that posed a diagnostic and management dilemma is reported. METHODS. Clinical records and histologic sections are examined. RESULT. Multiple syringomatous proliferations were noted around a basal cell carcinoma during Mohs surgery. A few foci were atypical appearing and focally extending into the deep dermis causing a diagnostic dilemma. All atypical syringomatous proliferations were excised. Evaluation of final Mohs margins by permanent sections and biopsies of normal-appearing facial skin showed multiple benign syringomas. CONCLUSION. Although solitary subclinical syringomas have been described in association with basal cell carcinomas, the occurrence of multiple syringomas and syringomatous proliferations has not been previously reported. Dermatologists should be aware of the existence of this phenomenon and consider permanent section evaluation to better determine nature of unusual incidental tumors identified in frozen sections during Mohs surgery.
Keywords: adult; human tissue; middle aged; cancer surgery; histopathology; case report; cell proliferation; basal cell carcinoma; skin neoplasms; diagnosis, differential; facial neoplasms; incidental finding; frozen section; carcinoma, basal cell; mohs surgery; chemosurgery; multiple cancer; skin surgery; sweat gland neoplasms; humans; human; male; priority journal; article; multiple syringomatous proliferation; syringoma
Journal Title: Dermatologic Surgery
Volume: 30
Issue: 11
ISSN: 1076-0512
Publisher: Lippincott Williams & Wilkins  
Date Published: 2004-11-01
Start Page: 1420
End Page: 1423
Language: English
DOI: 10.1111/j.1524-4725.2004.30439.x
PROVIDER: scopus
PUBMED: 15522025
DOI/URL:
Notes: Dermatol. Surg. -- Cited By (since 1996):5 -- Export Date: 16 June 2014 -- CODEN: DESUF -- Source: Scopus
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  1. Kishwer S Nehal
    279 Nehal
  2. Dana L Sachs
    23 Sachs
  3. Klaus J Busam
    689 Busam