Percutaneous vertebroplasty for treatment of osteolytic metastases of the C2 vertebral body using anterolateral and posterolateral approach Journal Article


Authors: Sun, G.; Jin, P.; Li, M.; Liu, X.; Li, F.; Yu, A. K. F.; Lu, Y.
Article Title: Percutaneous vertebroplasty for treatment of osteolytic metastases of the C2 vertebral body using anterolateral and posterolateral approach
Abstract: Percutaneous vertebroplasty (PVP) of C2 vertebral body is a challenging procedure. The aim of this retrospective study was to evaluate the feasibility, safety, and efficacy of PVP for the C2 osteolytic metastases using anterolateral and posterolateral approaches. Ten patients (8 male, 2 female) with C2 metastases were treated with PVP under local anesthesia. Anterolateral route was used under the guidance of fluoroscopy in 9 cases, and posterolateral route was used under the guidance of CT in 1 case. Pain intensity was scored on a scale ranging from 0/10 (no pain) to 10/10 (maximum pain intensity). The mean volume of cement injected was 3 ± 0.8 mL (range, 2.0-4.0 mL), with average vertebral filling of more than 70%. Cement leakage was detected in 4 treated vertebrae. Pain improvement and spine stability were achieved in all patients. In conclusion, PVP of C2 using anterolateral approach is a feasible and minimal invasive procedure for treatment of patients with C2 osteolytic metastases. Posterolateral approach is a safe and effective option for PVP of C2 when hyperextension of the cervical spine is contraindicated or difficult to achieve. ©Adenine Press (2010).
Keywords: adult; clinical article; aged; aged, 80 and over; middle aged; cancer surgery; osteolysis; retrospective studies; follow-up studies; neoplasm staging; computer assisted tomography; lung neoplasms; tomography, x-ray computed; breast neoplasms; retrospective study; urinary bladder neoplasms; odynophagia; feasibility studies; spinal neoplasms; neoplasm metastasis; radiography, interventional; image processing, computer-assisted; pain assessment; spine metastasis; fluoroscopy; bone cement; vertebra body; c2; percutaneous vertebroplasty; spine stabilization; bone cements; vertebroplasty
Journal Title: Technology in Cancer Research & Treatment
Volume: 9
Issue: 4
ISSN: 1533-0346
Publisher: Sage Publications, Inc.  
Date Published: 2010-08-01
Start Page: 417
End Page: 422
Language: English
PUBMED: 20626207
PROVIDER: scopus
DOI/URL:
Notes: --- - "Export Date: 20 April 2011" - "CODEN: TCRTB" - "Source: Scopus"
Citation Impact
MSK Authors
  1. Yang Lu
    11 Lu
  2. Alice Yu
    4 Yu