Bipolar radiofrequency ablation of painful spinal bone metastases performed under local anesthesia: Feasibility regarding patient’s experience and pain outcome Journal Article


Authors: Kastler, A.; Barbé, D. A.; Alemann, G.; Hadjidekov, G.; Cornelis, F. H.; Kastler, B.
Article Title: Bipolar radiofrequency ablation of painful spinal bone metastases performed under local anesthesia: Feasibility regarding patient’s experience and pain outcome
Abstract: Background and objectives: To assess the pain relief of bipolar RFA combined or not with vertebroplasty in patients with painful vertebral metastases and to evaluate the feasibility and tolerance of the RFA procedure performed under local anesthesia. Materials and Methods: 25 patients (18 men, 7 women, mean age: 60.X y.o) with refractory painful vertebral metastasis were consecutively included between 2012 and 2019. A total of 29 radiofrequency ablation (RFA) procedures were performed under CT guidance, local anesthesia and nitrous oxide inhalation, including 16 procedures combined with vertebroplasty for bone consolidation purposes. Pain efficacy was clinically evaluated using the visual analogue scale (VAS) at day 1, 1 month, 3 months, 6 months and 12 months, and the tolerance of the procedure was evaluated. Results: Procedure tolerance was graded as either not painful or tolerable in 97% of cases. Follow-up postprocedure mean VAS score decrease was 74% at day 1: 6.6 (p < 0.001), 79% at 1 month: 6.6 (p < 0.001), 79% at 3 months: 6.5 (p < 0.001), 77% at 6 months, and 79% at 12 months: 6.6 (p < 0.001). Conclusions: Bipolar RFA, with or without combined vertebroplasty, appears to be an effective and reliable technique for the treatment of refractory vertebral metastases in patients in the palliative care setting. It is a feasible procedure under local anesthesia which is well tolerated by patients therefore allowing to broaden the indications of such procedures. Field of study: interventional radiology. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
Keywords: palliative care; metastasis; radiofrequency ablation; local anesthesia; vertebroplasty; ct guidance
Journal Title: Medicina (Lithuania)
Volume: 57
Issue: 9
ISSN: 1010-660X
Publisher: MDPI  
Date Published: 2021-09-01
Start Page: 966
Language: English
DOI: 10.3390/medicina57090966
PROVIDER: scopus
PMCID: PMC8466129
PUBMED: 34577889
DOI/URL:
Notes: Article -- Export Date: 1 October 2021 -- Source: Scopus
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