Feasibility and safety of lateral and posterolateral percutaneous vertebroplasty of osteolytic C1–C2 lesions under computed tomography guidance and local anesthesia Journal Article
| Authors: | Guinebert, S.; Hayek, G.; Cornelis, F. H.; Torre, F.; Kastler, A.; Stacoffe, N.; Amoretti, N.; Bodard, S.; Kastler, B. |
| Article Title: | Feasibility and safety of lateral and posterolateral percutaneous vertebroplasty of osteolytic C1–C2 lesions under computed tomography guidance and local anesthesia |
| Abstract: | Purpose: To evaluate the safety and effectiveness of lateral or posterolateral percutaneous vertebroplasty (PVP) of osteolytic C1–C2 lesions performed under computed tomography (CT) guidance and local anesthesia. Materials and methods: A retrospective study of 16 consecutive patients (11 females and 5 males; aged from 24 to 86 years; median age, 65.5 years) who underwent 17 lateral or posterolateral PVP was performed. Pain status was assessed using a visual analog scale (VAS). Patients were evaluated preprocedurally as baseline and at 24 hours and 1, 6, and 12 months postprocedurally, until death, or until loss to follow-up. The Oswestry Disability Index was used to evaluate the patients’ functional disability preprocedurally. The adverse events were recorded using the Society of Interventional Radiology (SIR) classification. Results: The technical success was 100% (17/17) for a median Spinal Instability Neoplastic Score of 13.5 (interquartile range [IQR], 6.8, 20.3). Mean clinical follow-up was 10.1 months (range, 6–36 months; median, 19.5 months, IQR, 4, 35 months). Mean VAS score decreased significantly from 7.5 (SD ± 2.1) preprocedurally to 1.6 (SD ± 1.5) 24 hours postprocedurally, and 1.0 (SD ± 1.1), 1.5 (SD ± 1.0), and 0.5 (SD ± 1.5) at 1, 6, and 12 months, respectively (all P < .001). No severe adverse events were observed, but 3 cases of asymptomatic cement leakage were noted (SIR Grade 1; 17.6% [3/17]). Conclusions: Lateral and posterolateral PVP performed under CT guidance and local anesthesia is safe and effective to treat symptomatic osteolytic C1–C2 lesions. © 2024 SIR |
| Keywords: | adult; clinical article; controlled study; aged; middle aged; young adult; follow up; computer assisted tomography; retrospective study; feasibility study; paracetamol; tramadol; patient safety; scoring system; interventional radiology; lidocaine; visual analog scale; bone atrophy; comparative effectiveness; local anesthesia; percutaneous vertebroplasty; spinal instability neoplastic score; poly(methyl methacrylate); internal carotid artery; prone position; asymptomatic disease; vertebral artery; very elderly; human; male; female; article; ropivacaine; povidone; bone cement leakage; oswestry disability index; first cervical vertebra; lateral percutaneous vertebroplasty; posterolateral percutaneous vertebroplasty; second cervical vertebra |
| Journal Title: | Journal of Vascular and Interventional Radiology |
| Volume: | 35 |
| Issue: | 12 |
| ISSN: | 1051-0443 |
| Publisher: | Elsevier Science, Inc. |
| Date Published: | 2024-12-01 |
| Start Page: | 1778 |
| End Page: | 1784 |
| Language: | English |
| DOI: | 10.1016/j.jvir.2024.08.005 |
| PUBMED: | 39142517 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | The MSK Cancer Center Support Grant (P30 CA008748) is acknowledge in the PDF -- Source: Scopus |
