Effectiveness and cost-effectiveness of meaning-centered group psychotherapy in cancer survivors: Protocol of a randomized controlled trial Journal Article

Authors: van der Spek, N.; Vos, J.; van Uden-Kraan, C. F.; Breitbart, W.; Cuijpers, P.; Knipscheer-Kuipers, K.; Willemsen, V.; Tollenaar, R. A. E. M.; van Asperen, C. J.; Verdonck-de Leeuw, I. M.
Article Title: Effectiveness and cost-effectiveness of meaning-centered group psychotherapy in cancer survivors: Protocol of a randomized controlled trial
Abstract: Background: Meaning-focused coping may be at the core of adequate adjustment to life after cancer. Cancer survivors who experience their life as meaningful are better adjusted, have better quality of life and psychological functioning. Meaning-Centered Group Psychotherapy for Cancer Survivors (MCGP-CS) was designed to help patients to sustain or enhance a sense of meaning and purpose in their lives. The aim of the proposed study is to evaluate the effectiveness and cost-effectiveness of MCGP-CS.Methods/Design: Survivors diagnosed with cancer in the last 5 years and treated with curative intent, are recruited via several hospitals in the Netherlands. After screening, 168 survivors are randomly assigned to one of the three study arms: 1. Meaning-Centered Group Psychotherapy (MCGP-CS) 2. Supportive group psychotherapy (SGP) 3. Care as usual (CAU). Baseline assessment takes place before randomisation, with follow up assessments post-intervention and at 3, 6 and 12 months follow-up. Primary outcome is meaning making (PMP, PTGI, SPWB). Secondary outcome measures address quality of life (EORTC-30), anxiety and depression (HADS), hopelessness (BHS), optimism (LOT-R), adjustment to cancer (MAC), and costs (TIC-P, EQ-5D, PRODISQ).Discussion: Meaning-focused coping is key to adjustment to life after cancer, however, there is a lack of evidence based psychological interventions in this area. Many cancer survivors experience feelings of loneliness and alienation, and have a need for peer support, therefore a group method in particular, can be beneficial for sustaining or enhancing a sense of meaning. If this MCGP-CS is effective for cancer survivors, it can be implemented in the practice of psycho-oncology care.Trial registration: Netherlands Trial Register, NTR3571. © 2014 van der Spek et al.; licensee BioMed Central Ltd.
Keywords: controlled study; patient satisfaction; major clinical study; outcome assessment; follow up; quality of life; randomized controlled trial; evidence based practice; clinical protocol; cancer survivor; netherlands; depression; screening; survivorship; psycho-oncology; anxiety disorder; distress syndrome; emotion; coping behavior; clinical effectiveness; randomization; effectiveness; personal experience; meaning; cost-effectiveness; group therapy; loneliness; existential distress; peer group; adjustment; hopelessness; optimism; group psychotherapy; cancer; human; article; evaluation study; alienation
Journal Title: BMC Psychiatry
Volume: 14
Issue: 1
ISSN: 1471-244X
Publisher: Biomed Central Ltd  
Date Published: 2014-01-28
Start Page: 22
Language: English
DOI: 10.1186/1471-244x-14-22
PROVIDER: scopus
PMCID: PMC3942178
PUBMED: 24467861
Notes: Export Date: 1 May 2014 -- CODEN: BPMSC -- Source: Scopus
Citation Impact
MSK Authors
  1. William S Breitbart
    467 Breitbart