Long-term efficacy of meaning-centered group psychotherapy for cancer survivors: 2-year follow-up results of a randomized controlled trial Journal Article


Authors: Holtmaat, K.; van der Spek, N.; Lissenberg-Witte, B.; Breitbart, W.; Cuijpers, P.; Verdonck-de Leeuw, I.
Article Title: Long-term efficacy of meaning-centered group psychotherapy for cancer survivors: 2-year follow-up results of a randomized controlled trial
Abstract: Objective: Meaning-centered group psychotherapy for cancer survivors (MCGP-CS) is an effective intervention to improve personal meaning, psychological well-being, and depressive symptoms until 6 months after the intervention. In this study, the long-term effects of MCGP-CS (i.e., at 1- and 2-year follow-up) on meaning, psychological well-being and posttraumatic growth were assessed, in comparison to supportive group psychotherapy (SGP) and care as usual (CAU). Methods: Cancer survivors (n = 170) were randomized into MCGP-CS, SGP, or CAU. Assessments were scheduled at baseline, 1 week, 3 months, 6 months, 1 year, and 2 years postintervention. Outcome measures were the Personal Meaning Profile, Ryff's Scales of Psychological Well-Being (SPWB), the Posttraumatic Growth Inventory, and their subscales. Linear mixed models (LMM) were used and results were both reported on an intention-to-treat (ITT) basis, as well as for intervention completers only. Results: LMM and post hoc analyses with Bonferroni correction revealed that MCGP-CS participants reported more improvement on positive relations (subscale of SPWB) than CAU participants of 2-year postintervention (ITT analysis, Cohen's d =.82). Completers also reported more personal growth (subscale of SPWB) after MCGP-CS than after SGP 1-year postintervention (Cohen's d =.94). No long-term effects were found on the other outcome measures. Conclusions: In the 2 years after MCGP-CS, the short-term significant effects on personal meaning and most positive effects related to psychological well-being faded. However, MCGP-CS had a long-term positive effect on positive relations with others and on survivors' sense of personal growth. Trial registration: Netherlands Trial Register: NTR3571. © 2019 The Authors. Psycho-Oncology published by John Wiley & Sons Ltd.
Keywords: outcome assessment; follow-up studies; oncology; depression; cancer survivors; psychological stress; group psychotherapy; psychological adaptation; cancer; intention-to-treat analysis
Journal Title: Psycho-Oncology
Volume: 29
Issue: 4
ISSN: 1057-9249
Publisher: John Wiley & Sons  
Date Published: 2020-04-01
Start Page: 711
End Page: 718
Language: English
PMCID: PMC7199891
DOI: 10.1002/pon.5323
PROVIDER: scopus
PUBMED: 31876012
DOI/URL:
Notes: Article -- Export Date: 19 August 2020 -- CODEN: POJCE -- Source: Scopus
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  1. William S Breitbart
    460 Breitbart