Cost-utility analysis of meaning-centered group psychotherapy for cancer survivors Journal Article


Authors: van der Spek, N.; Jansen, F.; Holtmaat, K.; Vos, J.; Breitbart, W.; van Uden-Kraan, C. F.; Tollenaar, R. A. E. M.; Cuijpers, P.; Coupé, V. M.; Verdonck-de Leeuw, I. M.
Article Title: Cost-utility analysis of meaning-centered group psychotherapy for cancer survivors
Abstract: Background: Meaning-centered group psychotherapy for cancer survivors (MCGP-CS) improves meaning, psychological well-being, and mental adjustment to cancer and reduces psychological distress. This randomized controlled trial was conducted to investigate the cost-utility of MCGP-CS compared with supportive group psychotherapy (SGP) and care-as-usual (CAU). Methods: In total, 170 patients were randomized to MCGP-CS, SGP, or CAU. Intervention costs, direct medical and nonmedical costs, productivity losses, and health-related quality of life were measured until 6 months follow-up, using the TIC-P, PRODISQ, data from the hospital information system, and the EQ-5D. The cost-utility was calculated by comparing mean cumulative costs and quality-adjusted life years (QALYs). Results: Mean total costs ranged from €4492 (MCGP-CS) to €5304 (CAU). Mean QALYs ranged.507 (CAU) to.540 (MCGP-CS). MCGP-CS had a probability of 74% to be both less costly and more effective than CAU, and 49% compared with SGP. Sensitivity analyses showed these findings are robust. If society is willing to pay €0 for one gained QALY, MCGP-CS has a 78% probability of being cost-effective compared with CAU. This increases to 85% and 92% at willingness-to-pay thresholds of €10 000 and €30 000, which are commonly accepted thresholds. Conclusions: MCGP-CS is highly likely a cost-effective intervention, meaning that there is a positive balance between the costs and gains of MCGP-CS, in comparison with SGP and CAU. Copyright © 2018 John Wiley & Sons, Ltd.
Keywords: adult; cancer survival; controlled study; major clinical study; follow up; sensitivity analysis; randomized controlled trial; oncology; cancer survivor; cost effectiveness analysis; probability; meaning; quality adjusted life year; cost-effectiveness; group therapy; psychotherapy; existential; cost utility analysis; hospital information system; group psychotherapy; cancer; human; male; female; article; cost-utility analysis; meaning-centered psychotherapy; mcgp
Journal Title: Psycho-Oncology
Volume: 27
Issue: 7
ISSN: 1057-9249
Publisher: John Wiley & Sons  
Date Published: 2018-07-01
Start Page: 1772
End Page: 1779
Language: English
DOI: 10.1002/pon.4726
PROVIDER: scopus
PMCID: PMC6043397
PUBMED: 29624807
DOI/URL:
Notes: Article -- Export Date: 1 August 2018 -- Source: Scopus
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MSK Authors
  1. William S Breitbart
    335 Breitbart