Randomized clinical trials in pancreatic adenocarcinoma Journal Article

  


Authors: Rudloff, U.; Maker, A. V.; Brennan, M. F.; Allen, P. J.
Article Title: Randomized clinical trials in pancreatic adenocarcinoma
Abstract: This article critically reviews and ranks 107 prospective, randomized controlled trials (RCT) for pancreatic adenocarcinoma published between 2000 and 2008 identified through a standard MEDLINE literature search strategy, according to a standardized, previously published 3-tiered system (Ia, Ib, and Ic). All trials included in this article are Ia or Ib. Types of treatment reviewed include surgery, chemotherapy, molecular therapy, radiation therapy, immunotherapy, and palliative therapy. © 2010 Elsevier Inc. All rights reserved.
Keywords: cancer survival; treatment outcome; surgical technique; unclassified drug; clinical trial; review; end to end anastomosis; cisplatin; erlotinib; fluorouracil; placebo; cancer combination chemotherapy; drug efficacy; monotherapy; recommended drug dose; unspecified side effect; capecitabine; gemcitabine; cancer adjuvant therapy; cancer radiotherapy; pancreas cancer; pancreas resection; pancreatic neoplasms; antineoplastic agent; lymphadenectomy; pancreaticoduodenectomy; adenocarcinoma; imatinib; alpha2b interferon; unindexed drug; low drug dose; bortezomib; computer assisted tomography; controlled clinical trial; multiple cycle treatment; bleeding; randomized controlled trial; randomized controlled trials as topic; continuous infusion; cetuximab; docetaxel; irinotecan; drug cost; electron therapy; diagnostic value; randomized controlled trials; folinic acid; diabetes mellitus; drug response; tipifarnib; patient compliance; pancreas adenocarcinoma; gastrectomy; stent; total parenteral nutrition; intermethod comparison; epirubicin; octreotide; axitinib; aspiration biopsy; mitomycin; oxaliplatin; pemetrexed; literature review; exatecan; endoscopic echography; marimastat; 4 n acetyldinaline; cilengitide; enteric feeding; stomach obstruction; level ia evidence; pancreas fistula; pancreaticojejunostomy; drug intermittent therapy; 5 chloro 2,4 dihydroxypyridine plus oxonate potassium plus tegafur; gastrazole; jb 05008; tanomastat; ursodeoxycholic acid; endoscopic sphincterotomy; gastrojejunostomy; stent thrombosis
Journal Title: Surgical Oncology Clinics of North America
Volume: 19
Issue: 1
ISSN: 1055-3207
Publisher: Elsevier Inc.  
Date Published: 2010-01-01
Start Page: 115
End Page: 150
Language: English
DOI: 10.1016/j.soc.2009.09.009
PUBMED: 19914563
PROVIDER: scopus
DOI/URL:

http://www.scopus.com/inward/record.url?eid=2-s2.0-70449713475&partnerID=40&md5=f618dd55204dc97be6b942a7e59ba272
Notes: --- - "Cited By (since 1996): 2" - "Export Date: 20 April 2011" - "CODEN: SOCAF" - "Source: Scopus"
Altmetric
What is Altmetric?
Citation Impact
What is Dimensions Citation Badge?
BMJ Impact Analytics
MSK Authors
  1. Murray F Brennan
    1059 Brennan
  2. Ajay V Maker
    10 Maker
  3. Udo Rudloff
    12 Rudloff
  4. Peter Allen
    501 Allen
Related MSK Work