Imaging and management of a small cell lung cancer metastasis/adrenal adenoma collision tumor: A case report and review of the literature Journal Article
| Authors: | Untch, B. R.; Shia, J.; Downey, R. J.; Carrasquillo, J. A.; Panicek, D. M.; Strong, V. E. |
| Article Title: | Imaging and management of a small cell lung cancer metastasis/adrenal adenoma collision tumor: A case report and review of the literature |
| Abstract: | Objective: We report a case of an adrenal collision tumor composed of a small cell lung carcinoma metastasis and a benign adrenal adenoma identified preoperatively on FDG-PET, CT and MRI and confirmed pathologically.Methods: The patient's history, preoperative imaging characteristics, postoperative course, and histopathology are described. A review of the literature addressing adrenal collision tumors is provided.Results: A 47-year-old female was found to have a left upper lobe lung mass and an adrenal lesion on imaging. FDG-PET, CT and MRI of the adrenal suggested a metastatic lesion adjacent to an adrenal adenoma. CT-guided biopsy of the adrenal gland was consistent with a small cell lung cancer metastasis. The patient underwent systemic chemotherapy and had complete resolution of the left upper lobe mass. Post-treatment FDG-PET demonstrated a persistently enlarged adrenal gland with decreased but persistent FDG uptake. The patient underwent adrenalectomy and pathologic examination demonstrated a small cell lung cancer/adenoma collision tumor.Conclusions: This case and a review of the literature demonstrate that FDG, CT and MR imaging can all characterize the separate components of collision tumors within the adrenal gland. © 2014 Untch et al.; licensee BioMed Central Ltd. |
| Keywords: | immunohistochemistry; adult; cancer chemotherapy; middle aged; antibiotic therapy; histopathology; case report; postoperative period; cisplatin; nuclear magnetic resonance imaging; positron emission tomography; antineoplastic agent; laparoscopic surgery; computer assisted tomography; etoposide; body weight; coughing; lung metastasis; lung small cell cancer; preoperative period; drug uptake; cancer cell; cancer size; chromogranin; fluorodeoxyglucose; lymphadenopathy; small cell lung cancer; thyroid transcription factor 1; hoarseness; medical history; lung lobe; pancreas metastasis; adrenalectomy; collision tumor; human; female; article; adrenal adenoma; adrenal mass; fluorodeoxyglucose positron emission tomography; adrenal biopsy; adrenal cortex adenoma |
| Journal Title: | World Journal of Surgical Oncology |
| Volume: | 12 |
| Issue: | 1 |
| ISSN: | 1477-7819 |
| Publisher: | Biomed Central Ltd |
| Date Published: | 2014-02-26 |
| Start Page: | 45 |
| Language: | English |
| DOI: | 10.1186/1477-7819-12-45 |
| PROVIDER: | scopus |
| PMCID: | PMC3941693 |
| PUBMED: | 24571800 |
| DOI/URL: | |
| Notes: | Export Date: 2 April 2014 -- Source: Scopus |
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