Outcomes of operative sperm retrieval strategies for fertility preservation among males scheduled to undergo cancer treatment Journal Article


Authors: Berookhim, B. M.; Mulhall, J. P.
Article Title: Outcomes of operative sperm retrieval strategies for fertility preservation among males scheduled to undergo cancer treatment
Abstract: Objective To describe the outcomes of electroejaculation (EEJ) and testicular sperm extraction (TESE) performed for fertility preservation among male patients who are unable to ejaculate or have nonobstructive azoospermia/severe oligospermia before definitive cancer therapy. Design Retrospective cohort study. Setting Tertiary cancer referral center. Patient(s) Forty-nine patients seeking fertility preservation before definitive cancer therapy, with anejaculation, religious or cultural objections to masturbation, azoospermia, or severe oligospermia requiring either EEJ or TESE. Intervention(s) EEJ and TESE. Main Outcome Measure(s) Sperm retrieval rates. Result(s) Fifty-nine percent of patients overall and 60% of adolescents/young adults had sperm retrieved for cryopreservation. EEJ was successful in retrieving sperm in 60% of adolescents. Of all adolescents and young adults undergoing TESE, 33% had sperm retrieved for cryopreservation. No complications were reported. Chemotherapy was commenced without delay in all patients requiring it, frequently on the same day as the sperm retrieval. Conclusion(s) EEJ and TESE can be safely and successfully used for fertility preservation before cancer therapy among boys and young adult men who are unable to provide a semen specimen or have nonobstructive azoospermia, and they should be considered in all men meeting this patient profile. © 2014 American Society for Reproductive Medicine, Published by Elsevier Inc.
Keywords: adolescent; fertility preservation; testicular sperm extraction; cancer; electroejaculation
Journal Title: Fertility and Sterility
Volume: 101
Issue: 3
ISSN: 0015-0282
Publisher: Elsevier Science, Inc.  
Date Published: 2014-03-01
Start Page: 805
End Page: 811
Language: English
DOI: 10.1016/j.fertnstert.2013.11.122
PROVIDER: scopus
PUBMED: 24424372
DOI/URL:
Notes: Export Date: 2 April 2014 -- CODEN: FESTA -- Source: Scopus
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  1. John P Mulhall
    459 Mulhall