Options for fertility preservation in men and boys with cancer Journal Article


Authors: Stahl, P. J.; Stember, D. S.; Mulhall, J. P.
Article Title: Options for fertility preservation in men and boys with cancer
Abstract: Fertility is a critical quality of life issue in young men faced with a new diagnosis of malignancy. Fortunately, many options are available for the acquisition and storage of sperm, and fertility preservation is possible in the majority of cases. In this chapter we review the reproductive toxicities of cancer and cancer therapy, and the clinical management of young men whose fertility is threatened by cancer. The optimal utilization of sperm banking and strategies for fertility preservation in men with ejaculatory dysfunction and azoospermia are discussed. Lastly, emerging options for fertility preservation in pre-pubertal boys are reviewed. © 2012 Springer Science+Business Media B.V.
Keywords: cancer chemotherapy; leukemia; cancer surgery; busulfan; prednisone; cisplatin; doxorubicin; fluorouracil; alpha interferon; gemcitabine; cancer patient; cancer radiotherapy; radiation dose; methotrexate; glioma; colorectal cancer; lymphadenectomy; disease association; etoposide; alkylating agent; cyclophosphamide; vincristine; radiation injury; bladder cancer; carmustine; ifosfamide; procarbazine; vinblastine; high risk patient; hodgkin disease; sarcoma; postoperative complication; cryopreservation; nonhodgkin lymphoma; surgical risk; platinum complex; abdominal surgery; kidney cancer; testis cancer; germ cell tumor; chlorambucil; reproductive toxicity; retroperitoneum; pelvis surgery; mercaptopurine; male infertility; male fertility; spermatozoon count; azoospermia; sperm preservation; reproductive procedures; sperm donor; testicular sperm extraction
Journal Title: Advances in Experimental Medicine and Biology
Volume: 732
ISSN: 0065-2598
Publisher: Springer  
Date Published: 2012-01-01
Start Page: 29
End Page: 39
Language: English
DOI: 10.1007/978-94-007-2492-1_3
PROVIDER: scopus
PUBMED: 22210250
DOI/URL:
Notes: Chapter 3 in "Reproductive Health and Cancer in Adolescents and Young Adults" (ISBN: 978-94-007-2491-4) - "Export Date: 1 March 2012" - "CODEN: AEMBA" - "Source: Scopus"
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  1. John P Mulhall
    602 Mulhall
  2. Doron Sol Stember
    22 Stember