Overwhelming disseminated herpes simplex virus type 2 infection in a patient with severe burn injury: Case report and literature review Journal Article
| Authors: | Peppercorn, A.; Veit, L.; Sigel, C.; Weber, D. J.; Jones, S.; Cairns, B. A. |
| Article Title: | Overwhelming disseminated herpes simplex virus type 2 infection in a patient with severe burn injury: Case report and literature review |
| Abstract: | Viral-mediated organ disease is an infrequent but recognized complication of severe burn injury. This occurs primarily because of herpes family viruses such as cytomegalovirus, herpes simplex virus (HSV), and Epstein-Barr virus given their ability to establish lifelong latency after primary infection and reactivate in the setting of altered immune function. In this report, we describe a severely burned patient who succumbed to fulminant HSV-2 pneumonitis and hepatitis, and summarize the existing literature on HSV infections in this unique patient population. To our knowledge, this is the first report of disseminated visceral HSV-2 infection in a burn patient in the medical literature. Copyright © 2010 by the American Burn Association. |
| Keywords: | adult; clinical feature; disease course; case report; aciclovir; herpes simplex; burn; virus hepatitis; virus latency; foscarnet; cytomegalovirus; african american; epstein barr virus; virus pneumonia; virus reactivation; herpes simplex virus 2 |
| Journal Title: | Journal of Burn Care & Research |
| Volume: | 31 |
| Issue: | 3 |
| ISSN: | 1559-047X |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2010-05-01 |
| Start Page: | 492 |
| End Page: | 498 |
| Language: | English |
| DOI: | 10.1097/BCR.0b013e3181db51cb |
| PROVIDER: | scopus |
| PUBMED: | 20453737 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 20 April 2011" - "Source: Scopus" |
