Abstract: |
Breast cancer metastases to the eye are unusual in clinical oncology practice, but for the ophthalmologist, this entity represents both the most common type of malignant problem (metastatic cancer) diagnosed in the human eye, and the most common primary cancer (breast) to spread to the eye [1, 2]. The globe itself represents the anatomic structure most frequently diagnosed with an ocular metastasis. The uveal tract of the eye, composed of the iris, the ciliary body, and the choroidal layer, with its rich vascular network, is the site in the globe involved with the large majority of ocular metastatic disease. Rarely, other ophthalmic structures including the optic disc, conjunctiva, lacrimal gland, and extrabulbar structures such as orbital fat, muscle, nerve, and bone, are also diagnosed as sites of metastatic breast cancer. © Springer-Verlag Berlin Heidelberg 2006. |