Ophthalmic, ultrasonographic findings in primary central nervous system lymphoma with ocular involvement Journal Article


Authors: Ursea, R.; Heinemann, M. H.; Silverman, R. H.; Deangelis, L. M.; Daly, S. W.; Coleman, D. J.
Article Title: Ophthalmic, ultrasonographic findings in primary central nervous system lymphoma with ocular involvement
Abstract: Purpose: To describe and classify ophthalmic, ultrasonographic findings in patients with primary central nervous system lymphoma with ocular involvement. Methods: B- and A-scan ultrasonography was performed on the eyes of 13 patients with primary central nervous system lymphoma with ocular involvement. Results: In seven patients, the eyes were the site of initial involvement. In the other six patients, both ocular and central nervous system disease were present at the initial evaluation. All patients had abnormal ultrasonographic findings. The most common were vitreous debris (n = 10), choroidal-scleral thickening (n = 6), and widening of the optic nerve (n = 4). Elevated chorioretinal lesions (n = 3) and retinal detachment (n = 2) were also found. Conclusion: Ophthalmic ultrasonography is a useful adjunctive diagnostic technique for characterizing ocular involvement in lymphoma. Ocular lymphoma may present as chorioretinitis, vitreitis and nonspecific uveitis; it produces characteristic, but nonspecific findings on ultrasonography. The diagnosis of ocular involvement is an important factor in determining treatment.
Keywords: adolescent; adult; clinical article; aged; middle aged; brain neoplasms; antineoplastic combined chemotherapy protocols; biopsy; central nervous system tumor; lymphoma; retina detachment; retina; choroid; optic nerve; ocular lymphoma; uveitis; central nervous system disease; vitreous body; central nervous system lymphoma; eye cancer; vitrectomy; eye neoplasms; b scan; anterior eye segment; optic nerve disease; chorioretinopathy; humans; human; male; female; article; opthalmic ultrasound; a scan
Journal Title: Retina
Volume: 17
Issue: 2
ISSN: 0275-004X
Publisher: Wolters Kluwer  
Date Published: 1997-01-01
Start Page: 118
End Page: 123
Language: English
PUBMED: 9143039
PROVIDER: scopus
DOI: 10.1097/00006982-199703000-00006
DOI/URL:
Notes: Article -- Export Date: 17 March 2017 -- Source: Scopus
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