Erectile function rehabilitation in the radical prostatectomy patient Journal Article


Authors: Mulhall, J. P.; Bella, A. J.; Briganti, A.; McCullough, A.; Brock, G.
Article Title: Erectile function rehabilitation in the radical prostatectomy patient
Abstract: Introduction. Prostate cancer is common and is being diagnosed in younger men now compared with two decades ago. Long-term functional outcomes are of significant importance to patient and impact upon the patient decision-making process regarding choice of therapy. Erectile function preservation (rehabilitation) has gained significant traction worldwide despite the absence of definitive evidence in its favor. Aim. To define the role of rehabilitation in the prostate cancer patient who has undergone radical prostatectomy (RP). Methods. A committee of five experts in the field from three countries was convened, and using a thorough analysis of the literature and the Delphi approach to expert opinion, recommendations were arrived at for clinicians treating men with prostate cancer before and after definitive surgical management. Results. Recommendations arrived at included: that clinicians should discuss prevalence rates, the pathophysiology of erectile dysfunction after RP and the predictors of erectile function recovery, that validated instruments should be used using the published cut-offs for normalcy, that rehabilitation be discussed with patients, and that they be informed that significant potential benefits may be associated with rehabilitation. Conclusions. The International Consensus of Sexual Medicine (ICSM) 2001 committee on rehabilitation after radical prostatectomy recommended that a discussion occur regarding rehabilitation in all patients undergoing or who have undergone RP. However, the committee recognized the absence of definitive data to date and could not comment on the optimal approach to rehabilitation at this time. Mulhall JP, Bella AJ, Briganti A, McCullough A, and Brock G. Erectile function rehabilitation in the radical prostatectomy patient. © 2010 International Society for Sexual Medicine.
Keywords: clinical trial; postoperative period; placebo; nonhuman; pathophysiology; cancer patient; evidence-based medicine; radiation; prevalence; patient education as topic; practice guideline; prostate cancer; preoperative period; prostatectomy; prostaglandin; urology; data analysis; practice guidelines as topic; collagen; medical society; delphi study; delphi technique; patient decision making; rehabilitation; erectile dysfunction; phosphodiesterase v inhibitor; prostaglandin e1; sildenafil; tadalafil; vardenafil; oxygenation; rehabilitation care; phosphodiesterase inhibitors; medical expert; penis erection; smooth muscle; intracavernosal injections; pde5 inhibitor; penile implantation
Journal Title: Journal of Sexual Medicine
Volume: 7
ISSN: 1743-6095
Publisher: Elsevier Inc.  
Date Published: 2010-04-01
Start Page: 1687
End Page: 1698
Language: English
DOI: 10.1111/j.1743-6109.2010.01804.x
PUBMED: 20388165
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 3" - "Export Date: 20 April 2011" - "Source: Scopus"
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  1. John P Mulhall
    602 Mulhall