Post-radical prostatectomy pharmacological penile rehabilitation: Practice patterns among the international society for sexual medicine practitioners Journal Article


Authors: Teloken, P. E.; Mesquita, G.; Montorsi, F.; Mulhall, J.
Article Title: Post-radical prostatectomy pharmacological penile rehabilitation: Practice patterns among the international society for sexual medicine practitioners
Abstract: Introduction. Despite the fact that there is minimal evidence-based data supporting it, the concept of pharmacological penile rehabilitation following radical prostatectomy (RP) is receiving great attention. Aim. To define attitudes and practice patterns of clinicians who were members of the International Society for Sexual Medicine (ISSM) and/or its affiliated societies. Methods. Members of the ISSM and its regional affiliates were invited to participate in a web-based survey. Main Outcome Measures. Demographic factors, current practice status, and opinions regarding post-RP erectile dysfunction and penile rehabilitation. The statistical methods used included chi-square, Student's t-tests, and logistic regression analysis. Results. Three hundred-one physicians from 41 countries completed the questionnaire (82% were urologists). Sixty-five percent of the responders had formal sexual medicine specialty training, 44% had uro-oncology specialty training, and 60% performed RPs. Eighty-seven percent performed some form of rehabilitation. As part of the primary rehabilitation strategy, 95% used phosphodiesterase type 5 inhibitors (PDE5), 30% used vacuum device, 75% used intracavernosal injections, and 9.9% used intraurethral prostaglandin. Fifty-four percent commenced rehabilitation immediately/just after urethral catheter removal, and 37% within the first 4 months after RP. Neither the number of years in medical practice, clinician age, nor country/region of practice differed between rehabilitation performers and nonperformers. With regard to the primary reason for avoiding rehabilitation: 50% responded said it is the cost; 25% said the fact that it is not evidence-based; and 25% said they were not familiar with the concept. Performing rehabilitation was positively associated with urologic oncology training (P = 0.03), performing RP (P < 0.001), and seeing over 50 post-RP patients per year (P = 0.011). Conclusions. Among ISSM members post-RP penile rehabilitation is widely practiced, commenced early, and based predominantly on PDE5 inhibitors and intracavernosal injections. Clinicians who perform RP or see over 50 such patients per year are the most likely to perform rehabilitation. Cost represents the most common reason for rehabilitation neglect. Teloken P, Mesquita G, Montorsi F, and Mulhall J. Post-radical prostatectomy pharmacological penile rehabilitation: Practice patterns among ISSM practitioners. © 2009 International Society for Sexual Medicine.
Keywords: aged; middle aged; postoperative period; patient selection; clinical practice; physician's practice patterns; logistic models; odds ratio; time factors; questionnaires; prostate cancer; confidence intervals; health care cost; questionnaire; data collection; medical education; prostatectomy; prostaglandin; medical specialist; radical prostatectomy; radiation therapy; purines; physician attitude; piperazines; health knowledge, attitudes, practice; erectile dysfunction; penile rehabilitation; phosphodiesterase v inhibitor; prostaglandin e1; sildenafil; tadalafil; vardenafil; rehabilitation care; phosphodiesterase inhibitors; impotence, vasculogenic; penis; sulfones; catheter removal; device therapy; intracavernous drug administration; urethral catheter; penile diseases
Journal Title: Journal of Sexual Medicine
Volume: 6
Issue: 7
ISSN: 1743-6095
Publisher: Elsevier Inc.  
Date Published: 2009-01-01
Start Page: 2032
End Page: 2038
Language: English
DOI: 10.1111/j.1743-6109.2009.01269.x
PUBMED: 19453918
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 5" - "Export Date: 30 November 2010" - "Source: Scopus"
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  1. John P Mulhall
    602 Mulhall