Radiological impact of the use of calcium hydroxylapatite dermal fillers Journal Article


Authors: Feeney, J. N.; Fox, J. J.; Akhurst, T.
Article Title: Radiological impact of the use of calcium hydroxylapatite dermal fillers
Abstract: Aim: To report a case series in which the radiological features of the subcutaneous use of calcium hydroxylapatite (CaHa) dermal fillers are described for the first time. Materials and methods: Five patients with facial hyperattenuating hypermetabolic subcutaneous lesions were identified on 2- [<sup>18</sup>F]-fluoro-2-deoxy-d-glucose (FDG) positron-emission tomography/computed tomography (PET/CT), who gave a history of facial injections to augment physical appearance. Correlation with additional imaging studies was performed. Results: All cases had subcutaneous high attenuation material on CT (range 280-700 HU), which was FDG avid on PET, with a standardized uptake value (SUV) range of 2.9-13.4. Magnetic resonance imaging (MRI) demonstrated a heterogeneous intermediate signal intensity subcutaneous lesion with enhancement post-gadolinium in one case. Conclusions: CaHa dermal filler is hyperattenuating on CT, hypermetabolic on FDG-PET imaging, of intermediate signal intensity on MRI, and is a potential cause of a false-positive imaging study. © 2009 The Royal College of Radiologists.
Keywords: adult; clinical article; aged; middle aged; reconstructive surgical procedures; retrospective studies; young adult; nuclear magnetic resonance imaging; positron emission tomography; magnetic resonance imaging; radiopharmaceuticals; computer assisted tomography; tomography, x-ray computed; fluorodeoxyglucose f 18; hypermetabolism; fluorodeoxyglucose f18; positron-emission tomography; filler; hydroxyapatite; false positive result; soft tissue defect; biocompatible materials; cosmetic techniques; durapatite; face; false positive reactions; injections, subcutaneous
Journal Title: Clinical Radiology
Volume: 64
Issue: 9
ISSN: 0009-9260
Publisher: W B Saunders Co Ltd  
Date Published: 2009-09-01
Start Page: 897
End Page: 902
Language: English
DOI: 10.1016/j.crad.2009.05.004
PUBMED: 19664480
PROVIDER: scopus
DOI/URL:
Notes: --- - "Cited By (since 1996): 1" - "Export Date: 30 November 2010" - "CODEN: CLRAA" - "Source: Scopus"
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  1. Josef J Fox
    71 Fox
  2. John Noel Feeney
    8 Feeney
  3. Timothy J Akhurst
    139 Akhurst