T-Cell project: An international, longitudinal, observational study of patients with aggressive peripheral T-cell lymphoma Journal Article


Authors: Federico, M.; Bellei, M.; Pesce, E.; Zucca, E.; Pileri, S.; Montoto, S.; Weisenburger, D. D.; Ruediger, T.; Ko, Y. H.; Liang, R.; Zinzani, P. L.; Connors, J. M.; Foss, F. M.; Horwitz, S. M.; Polliack, A.; Vose, J. M.
Article Title: T-Cell project: An international, longitudinal, observational study of patients with aggressive peripheral T-cell lymphoma
Abstract: Peripheral T-cell lymphomas (PTCLs) comprise a heterogeneous group of neoplasms that are derived from post-thymic lymphoid cells at different stages of differentiation and with different morphological patterns, phenotypes, and clinical presentations. PTCLs are highly diverse, reflecting the diverse cells from which they can originate and are currently sub-classified using World Health Organization (WHO) 2008 criteria. Peripheral T-Cell Lymphomas account for 5%-10% of all lymphoproliferative disorders in the Western hemisphere, with an overall incidence of 0.5-2 per 100,000 individuals per year, and have a striking epidemiological distribution, with higher incidence in Asia. The clinical features of PTCL are extremely heterogeneous. PTCLs express even more clinical diversity than B-cell non-Hodgkin's lymphomas, and there is a close, though not absolute, relationship between some unusual clinical features and certain histological subtypes.
Keywords: chemotherapy; outcome; epidemiology; t-cell lymphoma
Journal Title: Revista Brasileira de Hematologia e Hemoterapia
Volume: 31
Issue: SUPPL. 2
ISSN: 1516-8484
Publisher: Sociedade Brasileira de Hematologia e Hemoterapia  
Date Published: 2009-01-01
Start Page: 21
End Page: 25
Language: Portuguese
PROVIDER: scopus
DOI: 10.1590/S1516-84842009000800007
DOI/URL:
Notes: --- - "Cited By (since 1996): 1" - "Export Date: 30 November 2010" - "Source: Scopus"
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  1. Steven M Horwitz
    645 Horwitz