Too much Sonic, too few neurons Journal Article
| Authors: | Fasano, C. A.; Studer, L. |
| Article Title: | Too much Sonic, too few neurons |
| Abstract: | The floor plate can generate neurons, but does so only in the midbrain. New work shows that Shh suppresses floor plate neurogenesis, and that in the midbrain, Wnt downregulates Shh expression via canonical signaling through β-catenin. © 2009 Nature America, Inc. All rights reserved. |
| Keywords: | signal transduction; protein expression; phenotype; sonic hedgehog protein; hedgehog proteins; protein stability; neurons; cell lineage; transgenic mouse; nerve fiber; stem cells; short survey; upregulation; mesencephalon; mouse strain; beta catenin; cre recombinase; nestin; neurogenin 2; wnt protein; loss of function mutation; nerve cell culture; nervous system development; rhombencephalon; neurogenesis; stem cell niche |
| Journal Title: | Nature Neuroscience |
| Volume: | 12 |
| Issue: | 2 |
| ISSN: | 1097-6256 |
| Publisher: | Nature Publishing Group |
| Date Published: | 2009-02-01 |
| Start Page: | 107 |
| End Page: | 108 |
| Language: | English |
| DOI: | 10.1038/nn0209-107 |
| PUBMED: | 19172163 |
| PROVIDER: | scopus |
| DOI/URL: | |
| Notes: | --- - "Export Date: 30 November 2010" - "CODEN: NANEF" - "Source: Scopus" |
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