4C-ing the Igh landscape Journal Article


Authors: Nicolas, L.; Chaudhuri, J.
Article Title: 4C-ing the Igh landscape
Abstract: The assembly of antigen receptors in developing B lymphocytes is determined by the spatio-temporal organization of the immunoglobulin heavy chain locus (Igh). In this issue of Immunity, Medvedovic etal. (2013) provide a comprehensive dynamic view of the Igh locus architecture. © 2013 Elsevier Inc.
Keywords: nonhuman; animals; allele; gene locus; cell differentiation; immunoglobulin heavy chain; immunoglobulin variable region; short survey; rag1 protein; rag2 protein; gene switching; thymocyte; lymphocyte antigen receptor; dna cleavage; pre b lymphocyte; antibody diversity; immunoglobulin heavy chain gene; genes, immunoglobulin heavy chain; transcription factor pax5; dna end joining repair; gene rearrangement, b-lymphocyte, heavy chain; precursor cells, b-lymphoid
Journal Title: Immunity
Volume: 39
Issue: 2
ISSN: 1074-7613
Publisher: Cell Press  
Date Published: 2013-08-22
Start Page: 199
End Page: 201
Language: English
DOI: 10.1016/j.immuni.2013.08.014
PROVIDER: scopus
PUBMED: 23973215
PMCID: PMC4151457
DOI/URL:
Notes: --- - "Export Date: 1 October 2013" - "CODEN: IUNIE" - "Source: Scopus"
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