Authors: | Nicolas, L.; Chaudhuri, J. |
Article Title: | 4C-ing the Igh landscape |
Abstract: | The assembly of antigen receptors in developing B lymphocytes is determined by the spatio-temporal organization of the immunoglobulin heavy chain locus (Igh). In this issue of Immunity, Medvedovic etal. (2013) provide a comprehensive dynamic view of the Igh locus architecture. © 2013 Elsevier Inc. |
Keywords: | nonhuman; animals; allele; gene locus; cell differentiation; immunoglobulin heavy chain; immunoglobulin variable region; short survey; rag1 protein; rag2 protein; gene switching; thymocyte; lymphocyte antigen receptor; dna cleavage; pre b lymphocyte; antibody diversity; immunoglobulin heavy chain gene; genes, immunoglobulin heavy chain; transcription factor pax5; dna end joining repair; gene rearrangement, b-lymphocyte, heavy chain; precursor cells, b-lymphoid |
Journal Title: | Immunity |
Volume: | 39 |
Issue: | 2 |
ISSN: | 1074-7613 |
Publisher: | Cell Press |
Date Published: | 2013-08-22 |
Start Page: | 199 |
End Page: | 201 |
Language: | English |
DOI: | 10.1016/j.immuni.2013.08.014 |
PROVIDER: | scopus |
PUBMED: | 23973215 |
PMCID: | PMC4151457 |
DOI/URL: | |
Notes: | --- - "Export Date: 1 October 2013" - "CODEN: IUNIE" - "Source: Scopus" |