Focused regional FDG PET/CT detects more osseous metastases than does whole-body PET/CT Journal Article


Authors: Mojtahedi, A.; Solomon, S. B.; Ulaner, G. A.
Article Title: Focused regional FDG PET/CT detects more osseous metastases than does whole-body PET/CT
Abstract: A patient with melanoma underwent FDG PET/CT for surveillance of metastatic disease. The whole-body PET/CT scan demonstrated a single FDG-avid lesion in the left ilium, suggestive of an osseous metastasis. Because there was no corresponding CT abnormality, biopsy was planned using PET/CT guidance. The PET/CT for biopsy guidance focused over a single pelvic bed position demonstrated at least 12 FDG-avid osseous metastases, which were not apparent on the original whole-body PET/CT. This case highlights the limitations of whole-body PET/CT in the detection of small metastases and suggests that a PET/CT focused over a specific body region can improve the sensitivity of detecting small metastases.
Keywords: aged; bone neoplasms; bone tumor; case report; comparative study; melanoma; metastasis; pathology; diagnostic agent; whole body imaging; fluorodeoxyglucose f 18; computer assisted emission tomography; fluorodeoxyglucose f18; scintiscanning; positron-emission tomography and computed tomography
Journal Title: Clinical Nuclear Medicine
Volume: 38
Issue: 3
ISSN: 0363-9762
Publisher: Lippincott Williams & Wilkins  
Date Published: 2013-03-01
Start Page: 217
End Page: 218
Language: English
PUBMED: 23357824
PROVIDER: scopus
DOI/URL:
Notes: --- - "Export Date: 4 September 2013" - "Source: Scopus"
Citation Impact
MSK Authors
  1. Gary Ulaner
    144 Ulaner
  2. Stephen Solomon
    390 Solomon