Ipilimumab-induced colitis on FDG PET/CT Journal Article
| Authors: | Lyall, A.; Vargas, H. A.; Carvajal, R. D.; Ulaner, G. |
| Article Title: | Ipilimumab-induced colitis on FDG PET/CT |
| Abstract: | A 52-year-old woman with metastatic melanoma was treated with ipilimumab. After 2 cycles of treatment, she developed watery diarrhea, sweats, and chills. An FDG PET/CT study demonstrated new FDG-avid (maximum standardized uptake value 15.6) diffuse colonic wall thickening, suggestive of ipilimumab-induced colitis. The patient was treated with systemic steroids, with subsequent resolution of her symptoms. Based on the response to steroids, the diagnosis of ipilimumab-induced enterocolitis was made. Ipilimumab may cause several immune-mediated toxicities, the most common of which is enterocolitis. Physicians interpreting FDG PET/CT examinations of patients treated with ipilimumab should be aware of these FDG-avid immune-mediated toxicities. © 2012 by Lippincott Williams & Wilkins. |
| Keywords: | adult; middle aged; case report; diarrhea; side effect; antineoplastic agents; ipilimumab; melanoma; multiple cycle treatment; steroid; chill; antibodies, monoclonal; computer assisted emission tomography; fluorodeoxyglucose f18; colitis; fluorodeoxyglucose; drug induced disease; fdg; sweating; positron-emission tomography and computed tomography |
| Journal Title: | Clinical Nuclear Medicine |
| Volume: | 37 |
| Issue: | 6 |
| ISSN: | 0363-9762 |
| Publisher: | Lippincott Williams & Wilkins |
| Date Published: | 2012-06-01 |
| Start Page: | 629 |
| End Page: | 630 |
| Language: | English |
| DOI: | 10.1097/RLU.0b013e318248549a |
| PROVIDER: | scopus |
| PUBMED: | 22614208 |
| DOI/URL: | |
| Notes: | --- - "Export Date: 4 June 2012" - "CODEN: CNMED" - "Source: Scopus" |
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144Ulaner -
148Carvajal -
7Lyall -
252Vargas Alvarez
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