Focal immunotherapy-induced pancreatitis mimicking metastasis on FDG PET/CT Journal Article

  


Authors: Das, J. P.; Halpenny, D.; Do, R. K.; Ulaner, G. A.
Article Title: Focal immunotherapy-induced pancreatitis mimicking metastasis on FDG PET/CT
Abstract: A 46-year-old man with metastatic lung adenocarcinoma was treated with pembrolizumab. FDG PET/CT was performed after 3 cycles of treatment and revealed a focal region of pancreatic tail enlargement with an SUVmax value of 7. Following treatment with corticosteroids and discontinuation of pembrolizumab, radiological resolution was observed, and a diagnosis of focal immunotherapy-induced pancreatitis was made. A unique spectrum of FDG-avid adverse events can develop in patients treated with immune-checkpoint inhibitors that may mimic metastatic disease. Knowledge of the radiologic features of these potential imaging pitfalls is crucial among those interpreting FDG PET/CT to allow prompt and decisive treatment.
Journal Title: Clinical Nuclear Medicine
Volume: 44
Issue: 10
ISSN: 0363-9762
Publisher: Lippincott Williams & Wilkins  
Date Published: 2019-10-01
Start Page: 836
End Page: 837
Language: English
DOI: 10.1097/rlu.0000000000002692
PUBMED: 31283599
PROVIDER: scopus
DOI/URL:

https://www.scopus.com/inward/record.uri?eid=2-s2.0-85071782954&doi=10.1097%2fRLU.0000000000002692&partnerID=40&md5=67175669ccf416f0ac899cc3cf6c4ddf
Notes: Article -- This is one of several "interesting images" features that the journal published in this issue -- Export Date: 1 October 2019 -- Source: Scopus
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MSK Authors
  1. Gary Ulaner
    147 Ulaner
  2. Kinh Gian Do
    257 Do
  3. Darragh Fintan Halpenny
    68 Halpenny
  4. Jeeban Paul Das
    43 Das
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